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Pakistan Journal of Pharmaceutical Sciences. 2015; 28 (5): 1777-1780
en Inglés | IMEMR | ID: emr-166673

RESUMEN

In this research study very first time a herbal ointment contain 10% Salvadora persica extract was compared with Solcosseryl jelly 10% and blank Vaseline to evaluate wound healing effects using excision wound healing model in animals. Three groups of rats [n-6] were experimentally wounded on the back of their neck. Group I was dressed with Vaseline containing 10% test drug, Group II was treated with thin layer of Solcoseryl jelly 10% as reference drug while Group III was dressed with thin layer of blank Vaseline as control group. The effect of vehicle on rate of wound healing were assessed and in all cases there were progressive decreased in wound area with time but wound dress with Vaseline containing S. persica extract and wound treated with Solcosseryl jelly significantly healed earlier than those treated with Vaseline. It is concluded that S. persica extract significantly enhance the acceleration rate of wound enclosure in rats


Asunto(s)
Animales de Laboratorio , Cicatrización de Heridas , Pomadas , Vaselina , Modelos Animales , Ratas
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