Studies on the potentiation analgesic effect of phenytoin and ketorolac with pelitazocine using albino mice by eddy's hot plate method

The analgesic activity was tested by Eddy's hot plate method in albino mice using combination of Pentazocine [1 mg/kg] with Phenytoin [10.20 mg/kg] and Pentazocine [1 mg/kg] with Ketorolac [10.20 mg/kg] was given by intra-peritoneal administration, The results showed a significant increase in reaction time [analgesia] in albino mice and hence the present study indicates that combination of Phenytoin and Ketorolac with Pentazocine has significant prolonged analgesic effect as compared with analgesic effect produced by Pentazocine alone

Analgesic and anti-inflammatory activity of aceclofenac Vs aceclofenac and paracetamol combination in animals

Analgesic and anti-inflammatory activity of aceclofenac was compared with combination of aceclofenac and paracetamol. The analgesic activity was assessed using Eddy's hot plate method and acetic acid-induced method. The anti-inflammatory activity was assessed in acute [Carrageenan-induced oedema] model of inflammation in rat. The aceclofenac and paracetamol combination showed significant analgesic and anti-inflammatory activity when compared to aceclofenac alone

Hepatoprotective activity of Clerodendron inerme extract

The ethanolic extract of dried leaves of Clerodendron inerme were screened pharmacologically for their hepatoprotective activity against Carbon tetrachloride-induced hepatotoxicity in rats. The ethanolic extract exhibited significant activity by lowering serum levels

Identification of sugars and estimation of water content in honey

Honey samples from country drug sellers, street vendors and tribes of Kanchipuram District were subjected to simple Thin Layer Chromatography [TLC] to identify sugars in those samples. Water content estimated by Karl Fischer titration method and refractive indices of the samples found to decrease with an increase in water content