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Rev. bras. cir. cardiovasc ; 35(5): 654-659, Sept.-Oct. 2020. tab
Artículo en Inglés | LILACS, SES-SP | ID: biblio-1137331

RESUMEN

Abstract Objective: To determine the association between the preoperative level of hemoglobin A1c (HbA1c) and in-hospital mortality in patients who underwent valvular heart surgery in our center in a retrospective cohort. Methods: In this retrospective consecutive cohort study, patients with type 2 diabetes mellitus who were referred to our center for elective valvular surgery were enrolled and followed up. The endpoint of this study was in-hospital mortality. Based on the level of HbA1c, patients were dichotomized around a level of 7% into two groups: exposed patients with HbA1c ≥ 7% and unexposed patients with HbA1c < 7%. Then, the study variables were compared between the two groups. Results: Two hundred twenty-four diabetic patients who were candidates for valvular surgery were enrolled; 106 patients (47.3%) had HbA1c < 7%, and 118 patients (52.6%) had HbA1c ≥ 7%. The duration of diabetes was higher in patients with HbA1c ≥ 7% (P=0.007). Thirteen (5.8%) patients died during hospital admission, of which nine patients were in the high HbA1c group. There was no significant difference between the groups regarding in-hospital mortality (P=0.899). Both the unadjusted and adjusted logistic regression models showed that HbA1c was not a predictor for in-hospital mortality (P=0.227 and P=0.388, respectively) Conclusion: This study showed no association between preoperative HbA1c levels and in-hospital mortality in candidates for valvular heart surgery.


Asunto(s)
Humanos , Masculino , Hemoglobina Glucada/análisis , Diabetes Mellitus Tipo 2 , Procedimientos Quirúrgicos Cardíacos , Glucemia , Inhibidores de la Enzima Convertidora de Angiotensina , Estudios Retrospectivos , Factores de Riesgo , Estudios de Cohortes , Mortalidad Hospitalaria , Antagonistas de Receptores de Angiotensina
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