1.
Artículo
en Inglés
| IMSEAR
| ID: sea-21298
RESUMEN
The mutagenic potential of phenytoin (PHT) was studied using the sister chromatid exchange (SCE) assay. Twenty nine PHT treated epileptics, 32 untreated and 32 normal healthy controls were analysed. Similar SCE frequencies were observed in untreated patients and patients on PHT monotherapy. Both groups had significantly increased SCE frequency as compared to controls. No positive correlation of SCE frequency with sex and duration of therapy was observed. The results of the present study suggest the role of the disease condition in inducing genetic damage as assessed by increased SCE frequencies.
Asunto(s)
Adolescente , Adulto , Epilepsia/tratamiento farmacológico , Femenino , Humanos , Masculino , Pruebas de Mutagenicidad , Fenitoína/efectos adversos , Intercambio de Cromátides Hermanas/efectos de los fármacos
2.
J Indian Med Assoc
;
1983 Dec; 81(11-12): 208-9
Artículo
en Inglés
| IMSEAR
| ID: sea-102616
Asunto(s)
Humanos , Cálices Renales , Enfermedades Renales , Pelvis Renal , Masculino , Persona de Mediana Edad , Rotura Espontánea
3.
J Indian Med Assoc
;
1983 Jul 1-16; 81(1-2): 15-6
Artículo
en Inglés
| IMSEAR
| ID: sea-96168
Asunto(s)
Adulto , Humanos , Malacoplasia/patología , Masculino , Enfermedades de la Vejiga Urinaria/patología
4.
J Indian Med Assoc
;
1980 Oct; 75(8): 166-7
Artículo
en Inglés
| IMSEAR
| ID: sea-96532