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1.
Clinics ; 72(4): 202-206, Apr. 2017. tab, graf
Artículo en Inglés | LILACS | ID: biblio-840062

RESUMEN

OBJECTIVES: To analyze the effects of motor learning on knee extension-flexion isokinetic performance in knee osteoarthritis patients. METHODS: One hundred and thirty-six middle-aged and older sedentary individuals (111 women, 64.3±9.9 years) with knee osteoarthritis (130 patients with bilateral) and who had never performed isokinetic testing underwent two bilateral knee extension-flexion (concentric-concentric) isokinetic evaluations (5 repetitions) at 60°/sec. The tests were first performed on the dominant leg with 2 min of recovery between test, and following a standardized warm-up that included 3 submaximal isokinetic repetitions. The same procedure was repeated on the non-dominant leg. The peak torque, peak torque adjusted for the body weight, total work, coefficient of variation and agonist/antagonist ratio were compared between tests. RESULTS: Patients showed significant improvements in test 2 compared to test 1, including higher levels of peak torque, peak torque adjusted for body weight and total work, as well as lower coefficients of variation. The agonist/antagonist relationship did not significantly change between tests. No significant differences were found between the right and left legs for all variables. CONCLUSION: The results suggest that performing two tests with a short recovery (2 min) between them could be used to reduce motor learning effects on clinical isokinetic testing of the knee joint in knee osteoarthritis patients.


Asunto(s)
Humanos , Masculino , Femenino , Persona de Mediana Edad , Anciano , Articulación de la Rodilla/fisiopatología , Fuerza Muscular/fisiología , Osteoartritis de la Rodilla/fisiopatología , Práctica Psicológica , Factores de Edad , Estudios Transversales , Contracción Muscular/fisiología , Músculo Esquelético/fisiología , Estadísticas no Paramétricas , Factores de Tiempo , Torque
2.
Journal of Veterinary Science ; : 27-34, 2010.
Artículo en Inglés | WPRIM | ID: wpr-160876

RESUMEN

This study was carried out to investigate fifteen cases of acute lethal infection of calves (< or = 4 months of age) by the protozoan parasite Theileria (T.) annulata in the south of Portugal. Calves developed multifocal to coalescent nodular skin lesions, similar to multicentric malignant lymphoma. Infestation with ticks (genus Hyalomma) was intense. Theileria was seen in blood and lymph node smears, and T. annulata infection was confirmed by isolation of schizont-transformed cells and sequencing of hypervariable region 4 of the 18S rRNA gene. At necropsy, hemorrhagic nodules or nodules with a hemorrhagic halo were seen, particularly in the skin, subcutaneous tissue, skeletal and cardiac muscles, pharynx, trachea and intestinal serosa. Histologically, nodules were formed by large, round, lymphoblastoid neoplastic-like cells. Immunohistochemistry (IHC) identified these cells as mostly CD3 positive T lymphocytes and MAC387 positive macrophages. A marker for B lymphocytes (CD79alphacy) labeled very few cells. T. annulata infected cells in these nodules were also identified by IHC through the use of two monoclonal antibodies (1C7 and 1C12) which are diagnostic for the parasite. It was concluded that the pathological changes observed in the different organs and tissues were caused by proliferation of schizont-infected macrophages, which subsequently stimulate a severe uncontrolled proliferation of uninfected T lymphocytes.


Asunto(s)
Animales , Bovinos , Femenino , Masculino , Secuencia de Bases , Enfermedades de los Bovinos/epidemiología , Procesos de Crecimiento Celular/fisiología , ADN Protozoario/química , Brotes de Enfermedades/veterinaria , Inmunohistoquímica/veterinaria , Linfocitos/parasitología , Datos de Secuencia Molecular , Reacción en Cadena de la Polimerasa/veterinaria , Portugal/epidemiología , ARN Ribosómico 18S/química , Análisis de Secuencia de ADN , Enfermedades de la Piel/epidemiología , Theileria annulata/aislamiento & purificación , Theileriosis/epidemiología
3.
Rev. Soc. Bras. Med. Trop ; 37(6): 476-479, nov.-dez. 2004. graf
Artículo en Portugués | LILACS | ID: lil-390703

RESUMEN

Em 1998, a Fundação de Medicina Tropical/Instituto de Medicina Tropical do Amazonas implementou o sistema de vigilância para síndromes febris agudas indiferenciadas, com o propósito de manter vigilância ativa e passiva na Amazônia Ocidental, Brasil, permitindo identificar e diagnosticar os agentes etiológicos causadores de febres agudas. O diagnóstico foi realizado através de estudos sorológicos para a detecção de anticorpos IgM, utilizando-se técnicas de ELISA (Enzyme-linked-immunosorbent assay) e kits ELISA comerciais. Foram analisadas 8.557 amostras de soros de pacientes com suspeita clínica de dengue, 40 por cento dos soros foram ELISA positivos para o vírus da dengue e 26 por cento dos soros foram ELISA positivos para outras doenças exantemáticas virais como rubéola, sarampo, parvovírus, oropouche e mayaro.


Asunto(s)
Humanos , Masculino , Femenino , Recién Nacido , Lactante , Preescolar , Niño , Adolescente , Adulto , Persona de Mediana Edad , Dengue , Virus del Dengue , Brotes de Enfermedades , Exantema , Anticuerpos Antivirales , Brasil , Ensayo de Inmunoadsorción Enzimática , Inmunoglobulina M , Estaciones del Año
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