Frequency of sensitivity to Parthenium hysterophorus in patients with chronic extensive eczematous eruption

Eczema is a pruritic skin disorder of exogenous or endogenous nature. Allergic contact dermatitis is of exogenous nature and can be caused by many allergens including plants. In this quasi-experimental study, 50 patients presenting with extensive eczematous eruption were enrolled. They were patch tested with fresh crushed extract of flowers of Parthenium hysterophorus. Three patch test readings were taken at 48 hours, 72 hours and 120 hours. Patch test readings were read according to ICDRG criteria. Forty four [88%] out of 50 enrolled patients were male while 6 [12%] were female with male to female ratio of 7.3:1. Average age of the patients was 56.8 years with S.D +/- 12.6 years. Fifty four percent of enrolled patients showed positive patch test reactions to fresh crushed extract of flowers of P. hysterophorus with a male to female ratio of 5.7:1. P. hysterophorus is a leading cause of extensive eczematous eruption of exogenous type in a specific group of patients

Papillo-incisal distance incisive papilla maxillary incisor distance in subjects of various arch forms

To compare the influence of various arch forms on papillo-incisal distance PID [distance between posterior limit of the incisive papilla and the most prominent contour of the labial surface of maxillary central incisors]. Descriptive study. Department of Prosthodontics, Lahore Medical and Dental College, Lahore, Pakistan, from October 2004-December 2005 and May2010-September2010. A total of 250 subjects, 125 male and 125 female were included. Theme of evaluation was incisive papilla maxillary central incisor distance and arch form. Normal healthy subjects with symmetrical arches and all teeth present except third molars were included. Subjects with malformed teeth, periodontal problems, orthodontic treatment or restorations on the labial tooth surfaces were excluded. Data was analyzed in SPSS 16 package by applying t test and ANOVA, with p

Cutaneous manifestations in 1000 Pakistani newborns

Cutaneous manifestations are commonly seen in neonates. Benign dermatoses in newborns must be distinguished from more serious, life threatening disorders with cutaneous manifestations. To determine the frequency of various dermatoses i.e. physiological and pathological among newborns up to 96 hours of age. 1000 full-term neonates were enrolled from labour rooms and pediatric nursery of Jinnah hospital, Lahore and were evaluated for cutaneous manifestations. All the relevant data regarding history, clinical examination and investigations were recorded and analyzed. Out of 1000 neonates, there were 469 boys and 531 girls. Their mean age was 72 hours [6-96 hrs]. Cutaneous manifestations were present in 94% of babies and 82.5% babies had more than one manifestation. The most common dermatoses were Mongolian spots [63.2%], Epstein pearls [47.8%], sebaceous hyperplasia [44.8%], miliaria [12.8%], hypertrichosis [12%], erythema toxicum neonatorum [12%], salmon patch [12%] and impetigo [11.4%]. Uncommon manifestations included desquamation 8.5%, omphalitis 8% and birth trauma [7.7%]. Rare dermatoses were hemangiomas [3.5%], cafe-au-lait macules [2.6%], congenital melanocytic nevus [2.4%], acne neonatorum [0.9%], preauricular skin tag [0.4%], cutis marmorata telangiectatica congenita and collodion baby in [0.1%] each. Cutancous manifestations one are frequent in newborns

Black dot tinea affecting the eyebrows in an adult female

Tinea capitis is the invasion of the hair by dermatophytic species. It is predominantly an infection of children, although adult cases have been reported particularly with Trichophyton tonsurans. We report an adult female patient with black dot variety of tinea capitis involving the eyebrows along with scalp, body and nails

Scleromyxedema in an HCV-positive male

Scleromyxedema is rare chronic cutaneous mucinosis usually associated with a monoclonal gammopathy and underlying systemic disease. We report a 42-year-old male who developed scleromyxedema and was also HCV positive

Vogt-koyanagi-harada syndrome: a case report and review of literature

Vogt-Koyanagi-Harada [VKH] syndrome is a rare multisystem disorder in which cell-mediated autoimmunity against melanocytes affects the eyes, inner ears, central nervous system and skin. Alopecia, poliosis and vitiligo are the cutaneous manifestations. Visual and hearing loss is the important complications which can be prevented by early diagnosis and aggressive systemic therapy. We report a case of VKH syndrome in which alopecia was the only cutaneous manifestation and early diagnosis and prompt systemic corticosteroid therapy prevented the visual loss and reduced the morbidity

Efficacy of puva therapy in moderate and severe chronic plaque psoriasis; a comparative study

OBJECTIVE: The aim of the study was to compare the efficacy of PUV A in terms of remission. dose and duration of treatment. in patients with moderate and severe psoriasis. PATIENTS AND METHOD: Forty patients [36 male and 4 females] of plaque type psoriasis were enrolled for a prospective and comparative study which was conducted in the department of dermatology, KEMC/Mayo Hospital Lahore. Twenty patients had moderate [30-60%] and the same number of patients had severe [60-90%] form of chronic plaque psoriasis. PUV A therapy was administered thrice weekly till 90% clearance was achieve. Final evaluation was made 18 weeks later. The two groups did not show significant difference in terms of treatments. CONCLUSIONS: Photo chemotherapy is an effective and economical procedure to clear chronic plaque psoriasis. There was no significant difference in response to treatment with respect to extent of the disease