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Clinics ; 66(5): 811-815, 2011. graf, tab
Artículo en Inglés | LILACS | ID: lil-593845

RESUMEN

OBJECTIVE: To evaluate the effects of three different target-controlled remifentanil infusion rates during target-controlled propofol infusion on hemodynamic parameters, pain, sedation, and recovery score during oocyte retrieval. METHODS: Sixty-nine women were scheduled for oocyte retrieval. Target-controlled propofol infusion at an effectsite concentration of 1.5 μg/mL was instituted. The patients were randomly allocated to receive remifentanil at an effect-site concentration of either 1.5 (group I, n = 23), 2 (group II, n = 23) or 2.5 ng/mL (group III, n = 23). Hemodynamic variables, sedation, pain, the Aldrete recovery score, and side effects were recorded. RESULTS: Hemodynamic variables, sedation and pain scores and the number of patients with the maximum Aldrete recovery score 10 min after the procedure were comparable among the groups. The number of patients in group III with the maximum Aldrete recovery score 5 min after the procedure was significantly lower than that in groups I and II. One patient in group II and one patient in group III suffered from nausea. CONCLUSION: Similar pain-free conscious sedation conditions without significant changes in hemodynamic parameters were provided by all three protocols. However, target controlled infusion of remifentanil at 1.5 or 2 ng/mL proved superior at providing early recovery compared to 2.5 ng/mL.


Asunto(s)
Adulto , Femenino , Humanos , Persona de Mediana Edad , Anestésicos Intravenosos/administración & dosificación , Recuperación del Oocito/métodos , Piperidinas/administración & dosificación , Propofol/administración & dosificación , Periodo de Recuperación de la Anestesia , Anestésicos Intravenosos/efectos adversos , Presión Sanguínea/efectos de los fármacos , Frecuencia Cardíaca/efectos de los fármacos , Infusiones Intravenosas , Dolor Postoperatorio , Náusea y Vómito Posoperatorios , Piperidinas/efectos adversos , Propofol/efectos adversos
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