Effect of the consumption on buriti oil on the metabolism of rats induced by iron overload

Objectives To compare the effect of the consumption of buriti oil and soybean oil on the metabolism of rats under stress induced by iron overload.Materials and methods A total of 28 rats were randomized into control groups who consumed diet added of soybean (CS) or buriti oil (CB) and gavage with saline and two experimental groups who consumed diet added of soybean (ES) or buriti oil (EB) and daily gavage with iron II sulfate as stress inducer. The fatty acid profile of diets was analyzed. Body weight and diet consumption were evaluated every two days. The lipid profile and liver weight of animals were evaluated at the end of the experiment.Results Diet added of soybean oil showed higher percentage of polyunsaturated fatty acids (45.6%) and diet with buriti oil was rich in monounsaturated fatty acids (66.9%). There were no differences in food intake, total cholesterol, HDL-cholesterol and LDL-cholesterol among groups (p > 0.05). However, animals fed with diet supplemented with buriti oil showed intermediate triglyceride levels (CB: 65 mg/dL; EB: 68.7 mg/dL) compared to ES group (102.5 mg/dL). The liver of rats from the CS group had higher weight (2.06 ± 0.2 g) compared to the CB group (1.56 ± 0.1 g).Conclusion Buriti oil consumption was able to minimize some changes related to iron overload.

SUPLEMENTAÇÃO COM MUCUNA PRURIENS ASSOCIADA AO TREINAMENTO DE FORÇA NÃO ALTERA CONSUMO ALIMENTAR, PESO CORPORAL E MEDIDAS MURINOMÉTRICAS EM RATOS TREINADOS / MUCUNA PRURIENS SUPPLEMENTATION ASSOCIATED WITH RESISTANCE TRAINING DOES NOT CHANGE FOOD INTAKE, BODY WEIGHT AND MURINOMETRIC VALUES IN TRAINED ANIMALS

RESUMOMucuna pruriens (MP) tem sido comercializada como suplemento para emagrecimento mesmo sem comprovação científica. Este estudo objetiva avaliar o efeito da MP associada ao treinamento resistido sobre parâmetros murinométricos e consumo alimentar em ratos. Os animais foram randomizados nos grupos: controle sedentário e treinado, MP sedentário e treinado. Os treinados executaram protocolo de saltos e os suplementados receberam 250 mg de MP/kg/dia via gavagem. O consumo alimentar e peso corporal foram avaliados semanalmente e medidas murinométricas ao final do protocolo. Não houve alterações no consumo alimentar (147 a 180 g), peso (341 a 368 g), comprimento (entre 24,6 e 25,5 cm), circunferências torácica (de 14,1 a 16,2 cm) e abdominal (variação de 14,5 a 15,8 cm), índice de massa corporal (entre 0,53 e 0,56 g/cm2) e índice de Lee (entre 4,5 e 4,8 cm3). Suplementação de MP associada ao exercício não altera consumo alimentar, peso e medidas murinométricas em ratos.

ABSTRACTMucuna pruriens(mp) has been marketed as a supplement for weight loss even without scientific proof. this study aims to evaluate the effect of mp supplementation associated with resistance training on murinometric parameters and food consumption in rats. animals were randomized into sedentary and control groups, supplemented with mp or not. trained animals performed the jump protocol and received the mp supplementation (250 mg/kg/day) by gavage. food consumption and body weight were assessed weekly and murinometric parameters, at the end of the protocol. there were no changes in food intake (147 - 180 g), weight (341 - 368 g), length (24.6 - 25.5 cm), chest (14.1 - 16.2 cm) and abdominal circumferences (14.5 - 15.8 cm), body mass index (0.53 - 0.56 g/cm2) and lee index (4.5 - 4.8 g/cm3). mp supplementation during exercise does not alter food intake, weight and murinometric measurements in rats.

Treinamento de força reduz perfil glicêmico de ratos / Resistance training reduces blood glucose in rats

Aim: To evaluate the effect of a ten-week strength training on the blood glucose of rats. Methods: Eighteen rats were divided into two groups: sedentary and trained. Trained animals underwent strength training for ten weeks. The animals performed four sets of eight jumps with intervals of 30 seconds during ten weeks with a frequency of 3 times per week. An overload weight was imposed to the animals, using appropriate vests, which increased every two weeks. Body weight and food consumption were evaluated weekly. At the end of the experiment, the animals were euthanized and theirblood glucose and weights of visceral fat and carcass were measured. Results: No changes were observed in body weight (359.29±38.56 g vs. 355±15.58 g), food intake (162.1±16.6 g vs 156.57±5.4 g) and weight of carcass (222.5±22.7 g vs 230.7±9.3 g), however, reduction of visceral fat (17.4±3.3 g vs 12.9±1.7 g) and blood glucose (180.0±21.9 mg/dL vs. 151.7±19.6 mg/dL) was observed in the trained animals. Conclusion: The protocol used in this study reduced visceral fat and blood glucose in animals subjected to strength training.

Objetivo: Avaliar o efeito de um treinamento de força de dez semanas sobre o perfil glicídico de ratos. Métodos: 18 ratos foram randomizados em dois grupos: sedentários e treinados. Os animais treinados foram submetidos a treinamento de força durante dez semanas. Os animais realizavam quatro séries de oito saltos com intervalos de 30 segundos, durante dez semanas, com frequência de três vezes por semana. Foi imposta uma sobrecarga de peso aos animais, utilizando-se coletes apropriados, aumentada quinzenalmente. Foram avaliados peso corporal e consumo alimentar semanalmente. Ao final do experimento, os animais foram eutanasiados e verificou-se glicemia, peso de gordura visceral e de carcaça. Resultados: Não foram observadas alterações no peso corporal (359,29 ± 38,56 g vs. 355 ± 15,58 g), consumo alimentar (162,1 ± 16,6 g vs. 156,57 ± 5,4 g) e peso da carcaça (222,5 ± 22,7 g vs. 230,7 ± 9,3 g), entretanto, encontrou-se redução da gordura visceral (17,4 ± 3,3 g vs. 12,9 ± 1,7 g) e da glicemia (180,0 ± 21,9 mg/dL vs. 151,7±19,6 mg/dL) nos animais treinados. Conclusão: O protocolo aplicado neste estudo reduziu gordura visceral e glicemia nos animais submetidos ao treinamento de força.

Associação de microburaco macular e fosseta de papila / Association of macular microhole and optic disc pit

A fosseta de papila do nervo óptico e o microburaco macular são duas patologias raras, cuja probabilidade de coexistência se torna extremamente baixa, embora não haja relação fisiopatológica entre ambas, descreveremos um caso de associação das mesmas, acometendo comumente um olho, a fim de analisar as manifestações clínicas, os exames de OCT, angiografia, retinografia, biomocroscopia, o tratamento e a correlação entre ambas patologias.

Optic disc pit and macular microhole are two rare pathologies with an extremely low likelihood of coexistence, this paper will report an association of both pathologies in the same eye with the purpose of analyzing clinical manifestations, tests, angiography, OCT, retinography, biomocroscopy, treatment outcome and the connection between the optic disc pit and macular microhole.