RESUMEN
Objective: To see the consequences of first trimester threatened miscarriage on maternal and fetal outcomes
Study design: A prospective case-control study
Place and duration: Study conducted at Ziauddin University and Hospitals Karachi from 1st January 2012 to 31st January 2013
Methodology: 100 females attending the Antenatal clinic with threatened miscarriage who matched the selection criteria were included as cases.106 women without any history of threatened miscarriage were selected as controls. These patients were then followed to evaluate complications in later pregnancy
Results: Women with threatened miscarriage were more prone to be delivering prematurely, experience pre labour premature rupture of membranes and to deliver babies with intrauterinegrowth restriction as compared to those women without any bleeding. Women with first trimester threatened miscarriage had a statistically significant higher likelihood of Antepartum haemorrhage [18%] as compared to controls [4.6%] and were found to be significantly associated with Pregnancy induced hypertension and preeclampsia. Regarding fetal outcomes it was found that higher rates of perinatal mortality were found in females with 1[st] trimester bleeding and more babies with congenital anomalies were born to these women
Conclusion: Threatened miscarriage during first trimester of pregnancy is a predictor of increased incidence of adverse maternal and fetal outcomes