Clinical Significance of HBV Detection in NHL Patients / 中国实验血液学杂志

<p><b>OBJECTIVE</b>To analyze the relation of HBV infection with clinical characteristics and prognosis in NHL patients, so as to explore the significance of HBV detection.</p><p><b>METHODS</b>Sixty-eight NHL patients from December 2013 to December 2016 were enrolled in NHL group and 136 patients with other malignancies were chosen in control group, the detectable rate of HBV was compared between 2 groups. The correlation of HBV infection with sex, age, stage, cell origin, expression of P53 and BCL-2 in NHL patients was analyzed. The prognosis-related factors in NHL patients were also analyzed.</p><p><b>RESULTS</b>The infection rate of HBV in NHL group was 51.47%(35/68), that in control group was 15.44% (21/136), and the difference was statistically significant(χ=27.768,P<0.05). HBV infection correlated with cell origins and expression of BCL-2 in NHL patients(P<0.05). The prognosis of NHL patients demonstrated no correlation with sex, age, cell origins and HBV infection (P>0.05), while the prognosis was significantly related with stage, expression of P53 and BCL-2(P<0.05).</p><p><b>CONCLUSION</b>HBV infection correlates with BCL-2 expression level of NHL patients, and shows influence on the prognosis of patients.</p>

Value of hsCRP and Alb in Evaluating the Prognosis of Patients with Systemic Lupus Erythematosus / 中国实验血液学杂志

<p><b>OBJECTIVE</b>To study the value of hsCRP and Alb in evaluating the prognosis of patients with systemic lupus erythematosus (SLE).</p><p><b>METHODS</b>126 SLE patients from January 2011 to January 2016 were enrolled in this study, and their clinical data were collected, including SLEDAI, hsCRP and Alb and complications. The correlation between hsCRP/Alb ratio and SLEDAI after treatment was analyzed. All patients were followed up after discharge, and the prognosis-related factors were analyzed.</p><p><b>RESULTS</b>After treatment, hsCRP/Alb ratio of patients with SLEDAI 10-14 score was significantly higher than that of 5-9 and 0-4 score(P<0.05). hsCRP/Alb ratio was positively correlated with infection (r=0.574), renal damage (r=0.499) and cardiac injury (r=0.516) (P<0.05), while it demonstrated no correlation with blood system damage, CNS damage and lung injury(P>0.05). after treatment SLEDAI ≥10 score, hsCRP/Alb≥0.05 mg/g and complications significantly correlated with prognosis of patients(P<0.05).</p><p><b>CONCLUSION</b>hsCRP/Alb correlates with the prognosis of patients with SLE at a certam level.</p>