Studies on the Absorptive Kinetics of Daidzeid Derivative DZ18in Rats'Small Intestines / 中国药房

OBJECTIVE:To study the mechanism and location of absorption of DZ18.METHODS:In this study,improved intestinal absorption experiments(in vivo,in vitro)were used to study the absorption of DZ18in rats.RESULTS:It was found that there was no significant difference in absorptive rate in rats between without and with bile duct ligation.The cumulative percentages of absorption were59.2%and58.8%.CONCLUSION:There are no significant differences among the absorptive rates at different parts of small intestine in rats,which shows that there is no specificity of intestinal segments in absorption.