RESUMEN
Mucormycosis, also referred to as Zygomycosis, is chiefly caused by filamentous molds belonging to the Mucorales group. It can be acquired through inhaling spores, consuming contaminated food, or through injury to the skin. Currently, the second most prevalent fungal infection disease is mucormycosis. It gained greatest attention following the COVID-19 pandemic. The review mainly focuses on several outlines like its history, epidemiology, pathophysiology, types, diagnosis and treatment of mucormycosis. In treatment of mucormycosis, conventional therapy against mucormycosis and some antifungal agents has been discussed. Several diverse contagious ailments were conventionally cured utilizing a widespread series of medicinal plants. Given that India is at the forefront of the Ayurvedic and Siddha medical systems, traditional herbal medicine from India is highly well-known. Antifungal chemicals derived from plants can be a viable option for developing novel and enhanced alternative formulations in the field of antifungal medicine. The main focus of the review is to explore the potential plants having the antifungal activity used for the treatment of mucormycosis. Some of the plants with antifungal activity have been explained, which includes garlic, tea tree oil, aloe vera, thyme, turmeric, neem, eucalyptus, clove, goldenseal, calendula, lavender, guduchi, and oregano. Animal models for mucormycosis study have been explained in the review.
RESUMEN
The last stage of many hepatic diseases, including hepatitis, is cirrhosis. The liver's vital function in detoxifying xenobiotics—such as medications and toxic composites—is the subject of much research. Liver cirrhosis is the cause of alterations in the liver's architecture that mostly affect protein binding, blood circulation, and the enzymes that break down medicinal substances. The main reason why therapeutic metabolising enzymes disappear is because to liver towel loss. However, not all enzyme activity is decreased in tandem; some are only changed in one specific case. This case report focuses on the clinical features, diagnostic evaluation, and therapeutic concerns of a patient having liver cirrhosis. Further research and advancements in our comprehension of the pathogenesis and treatment of cirrhosis are necessary in order to enhance outcomes and minimise the burden of this illness on those who are impacted.
RESUMEN
Osteoarthritis, also known as OA, is a type of joint degeneration characterized by changes in the morphology and biochemistry of the synovial membrane and joint capsule, as well as degradation of cartilage joint and expansion of the marginal bone. Inflammation causes the joints to deteriorate in a subtype of osteoarthritis called erosive OA. DIP (distal interphalangeal), PIP (proximal interphalangeal), CMC (carpometacarpal) and metacarpophalangeal (MCP) joints are the most often affected joints in the hand. Other joints in other body regions are extremely seldom affected. Our patient’s diagnosis report suggests erosive osteoarthritis and seronegative arthritis as negative anti-RF factors.