Prevalencia de la infección cervical por virus papiloma humano (HPV) en población caucásica y guaraní, residente en la provincia de Misiones, Argentina / [Prevalence of cervical infection by human papilloma virus (HPV) in the Caucasian and Guaraní populations residing in the province of Misiones, Argentina]

A genital infection with human papillomavirus (HPV) of a high risk type is necessary for the development of cervical carcinoma. HPV viral distribution among diverse world populations is not homogeneous, viral reservoirs having been detected in particular regions that can interact when humans engage in active contacts. Such viral dynamics alters the population cervical cancer relative risk, particularly when the prevalence of HPV oncogenic risk types is high. We have compared women exposed to different social, cultural and environmental conditions regarding cervical HPV infection, analyzing two populations from Misiones, Argentina: White urban women and--Guarani indian women living in the rain forest. Demographic, clinical and sexual behavior data were collected and cytological, colposcopical and virological analysis performed. Detection and genotypification of HPV was performed by PCR-RFLP. The prevalence for generic HPV infection found was high in both populations, urban women: 43

, with a statistically significant difference. These values were positively associated to age of first intercourse, number of male partners and smoking history. HPV type-specific prevalences showed a relative homogeneity between populations when the main representatives of the high risk (16 and 18: 23

) types were grouped together. However, the presence of other viral types was notoriously different, representing only 9

in urban women and 29

in Guarani indians with particularly high risk HPV types (33, 35, 39, 45, 51, 52, 58, 67, 68). This situation might be of importance for future viral dynamics, phylogenetic and vaccine formulation studies.

) and low risk (6 y 11: 12

Rinoscleroma - tratamento cirurgico. / Rhinoscleroma - surgical treatment

Os autores fazem um estudo retrospectivo do rinoscleroma, preconizando o tratamento cirurgico para erradicacao da doenca.Apresentam dois casos em que se optou pela cirurgia. O primeiro paciente era portador de extensa lesao que atingia o septo, asa do nariz, assoalho nasal e labio superior e o segundo apresentava volumosa tumoracao nasal

Melanoma maligno primitivo das fossas nasais.Apresentacao de um caso. / Primitive malignant melanoma of the nasal cavity. A case report

Os autores apresentam um caso de melanoma maligno primitivo das fossas nasais, descrevendo sua frequencia, local de implantacao, sintomatologia, diagnostico diferencial, prognostico e tratamento