RESUMEN
Comprehensively, nutrient deficiencies in humans and animals are a quiet epidemic in many underdeveloped nations. Nutrient deficiencies in humans and animals are a global problem in most developing countries. Lentil is one of the most important and nutritious Rabi pulse in India. It’s a leguminous crop that improves the soil fertility through biological nitrogen fixation. In this contest an experiment was conducted to study the enhancement of plant growth, chlorophyll content, flowering, yield and seed protein content by plant growth regulators in DPL-62 lentil (Lens culinaris L. Medik) variety during two Rabi seasons of 2019-20 and 2020-21. The field experiment was laid out in randomized block design (RBD). Five growth regulators viz. triiodobenzoic acid (TIBA), gibberellic acid (GA3), cytokinin, indole acetic acid (IAA), and naphthaleneacetic acid (NAA) were used in Eleven treatments were tested T1: Control, T2: 25 ppm TIBA, T3: 50 ppm TIBA, T4: 25 ppm GA3, T5: 50 ppm GA3, T6: 5 ppm Cytokinin, T7: 10 ppm Cytokinin, T8: 25 ppm IAA, T9: 50 ppm IAA, T10: 25 ppm NAA, T11: 50 ppm NAA. The results revealed that the maximum plant height (38.12 & 38.15 cm at harvest) was obtained by the 50 ppm GA3 followed by 50 ppm IAA (37.00 & 38.10 cm at harvest) spray at all stages. However, the 50 ppm TIBA showed better results (per plant) viz., number of branches (15.00, 15.33 at 110DAS), leaf area (86.50, 86.32 at 110DAS), number of pods (160.20, 160.37), pod setting (65.45, 65.50%), seed weight (2.02, 2.10g), test weight (27.32, 27.39g) and seed yield (1500.00, 1510.00 kg ha-1) of lentil as compared to all other treatments. The maximum days of flowering (67.50, 67.85) and days of maturity. On the basis of the observed results the growing of DPL-60 lentil variety with foliar applications of 50 ppm TIBA is recommended for the farmers of the test area for greater production and profitability.
RESUMEN
Clerodendrum serratum Linn. (Family: Verbenaceae) is very widely distributed in tropical and subtropical regions of the world. Ethno-medicinal importance of the plant has been reported in various indigenous systems of medicines like Ayurveda, Siddha and Unani for the treatment of various life-threatening diseases such as syphilis, typhoid, cancer, jaundice and hypertension. Some of the chief constituents found in the plant are D-mannitol, hispidulin, cleroflavone, apigenin, scutellarein, serratagenic acid, acteoside, verbascoside, oleanolic acid, clerodermic acid, γ-sitosterol, β-sitosterol, cholestanol, clerosterol, campesterol and 24-ethyl cholesterol. Traditionally, it has been also used as anti-rheumatic, anti-asthmatic, febrifuge, in cephalagia and ophthalmia. The roots of C. serratum are also used as anti-oxidant, anti-bacterial, and anti-fungal. Besides these the antimicrobial value of this herbal plant have also been reported in its stems and leaves. These reports are very encouraging and indicate that herb should be studied more expensively for its therapeutic benefits.
RESUMEN
Mucoadhesion had been a topic of interest in the design of drug delivery system to prolong the residence time of the dosage form with the under lying absorption surface to improve and enhance the bioavailability of drugs. Mucoadhesion occurs between two surfaces, one of which is a mucous membrane and another is drug delivery system. Pharmaceutical aspects of mucoadhesion had been the subject of great interest during recent years because mucoadhesion could be a solution for bioavailability problems that result from a too short length of stay of the pharmaceutical dosage form at the absorption site within the gastro-intestinal tract. It had been a great challenge to the pharmaceutical sciences in order to enhance localised drug delivery or to deliver ‘difficult’ molecules (proteins and oligonucleotides) into the systemic circulation. Mucoadhesive systems remain in close contact with the absorption tissue, the mucous membrane releasing the drug at the action site leading to increase in bioavailability (both local and systemic effects). Extending the residence time of a dosage form at a particular site and controlling the release of drug from the dosage form are useful especially for achieving controlled plasma level of the drug as well as improving bioavailability. The main objective of this study was to selectively collect the data which were extended the gastrointestinal residence time of the dosage form and controlled the release of mucoadhesives.