Clinico-epidemiological study of sexually transmitted infections in a tertiary centre at Aligarh

Objective: To highlight the pattern of sexually transmitted infections [STIs] and the profile of patients with HIV infection in STI patients as seen at our hospital

Methods: A retrospective analysis of records of patients attending the STD clinic during the period of September 2013 till August 2014 was done

Results: A total of 90 patients attended the STD clinic, out of which 63 were males and 27 were females with the male: female ratio of 2.3: 1. Maximum patients belonged to the age group of 20-30 years. Herpes genitalis was the most common ulcerative STI, 19 [21.1%] out of 90 patients had herpes genitalis. Genital warts were the most common non-ulcerative STI, 25 [27.8%] out of 90 patients had genital warts. HIV seropositivity was seen in 7 patients

Conclusion: Herpes genitalis was the most common ulcerative STI, while genital warts was the most common nonulcerative STI in our study. The prevalence of HIV among STI clients in India has been on the rise, which was also seen in our study

case of urticaria pigmentosa

Urticaria pigmentosa is the most common variant of cutaneous mastocytosis. A three and a half-month-old female child presented with generalized eruption of multiple brownish macular and papular lesions on the trunk, limbs, face and neck of two months duration. On stroking the individual lesion, there was formation of wheal and erythema [Darier's sign positive]. Histopathological examination of lesional skin and staining with Giemsa stain and hematoxylin eosin showed infiltration of numerous spindle shaped mast cells in perivascular and periappendageal location in the upper dermis. These findings were suggestive of mastocytosis. There was no systemic involvement. We present a typical case of urticaria pigmentosa

Metastatic testicular cancer in a patient with arsenical keratosis

Arsenicosis is a multisystem disorder, with many cutaneous features. The cutaneous manifestations take the form of pigmentary changes, hyperkeratosis, and skin cancers [Bowen's disease, squamous cell carcinoma, and basal cell carcinoma]. It is a known carcinogen and there is association between chronic arsenic exposure and malignancy of bladder, lung, liver, kidney and other visceral malignancies. Our patient came from an endemic area where levels of arsenic are high in drinking water and had features of arsenical keratosis for past fifteen years along with metastatic testicular cancer at the time of presentation. Arsenic exposure may increase the risk of testicular cancer