Retratos de medicamentos homeopáticos com repertório de sintomas / Portraits of homeopathic medicines with a repertoire of symptoms

A obra Retratos de Medicamentos Homeopáticos é um inestimável trabalho da Dra. Margaret Tyler que descreve 125 imagens de remédios retratadas com citações de Hahnemann, T. F. Allen, Hering, Burnett, Farrington, Kent, Clarke e outros autores de grande relevância, bem como a sua própria experiência. Para todos os medicamentos, a autora apresenta informações valiosas, incluindo o histórico de uso e preparação, e o estudo comparado de cada remédio com um ou mais medicamentos que se assemelham. Ela relata histórias interessantes e bem-humoradas, e coloca também a lista de sintomas mais importantes e indicações características. A inclusão de casos, artigos e cartas de várias fontes enriquece a imagem dos remédios e alarga o âmbito deste trabalho como uma referência muito útil para aqueles que desejam conhecer melhor os medicamentos da Matéria Médica Homeopática. Ao final, encontra-se um Repertório de Sintomas cuidadosamente elaborado para facilitar a utilização clínica desta obra.

Characterization of insecticidal peptides from venom Australian funnel-web spiders

Australian funnel-web spiders are relatively large primitive hunting spiders. Male Atrax robustus spiders have been responsible for a number of human deaths. Venom was collected from the species Hadronyche infensa (Hickman) [female], H. formidabilis [male and female], H. versuta [female], and A. robustus (Cambridge) [male] and was fractionated by high performance liquid chromatography. This resulted in the isolation and purification of a homologous series of 7 insecticidal peptides of relatively low molecular mass (approximately 4kDa). The amino acid sequences of these toxins consisted of 36 or 37 amino acids and were named atracotoxins. For the major bioassay of these toxins, we used the cotton bollworm, Helicoverpa armigera (Hubner), due to the great damage it causes to crops worldwide. These toxins, when injected subcutaneously into fifth or sixth instar larvae of Helicoverpa armigera,were lethal or caused an apparently irreversible writhing. The toxin from H. versuta venom showed no significant toxicity when subcutaneously injected into newborn mice. One of the toxins was found to have a free acid carboxyl terminus. These toxins have great potential as lead compounds for insecticide design or for incorporation in recombinant baculovirus insecticides.

Restoration of liver mass after partial hepatectomy - implications for living donor liver transplantation

Abstract In living donor liver transplantation; the recipient liver undergoes more rapid regeneration than the remnant liver in the donor. In this study we investigated the factors which may be responsible for the difference in the regenerative response between the donor and the recipient. Long Evans rats were subjected to either partial hepatectomy (PH) or sham operation (SH) and were treated with liver cytosol (C) and cyclosporine (Cy). The rats were sacrificed at 24; 48; 72 and 96 hours and 1 and 2 weeks postoperatively. The livers were removed to determine the liver weight/body weight (LW / BW) ratio and the mitotic index. The mitotic index; serum aspartate transferase (AST) and serum alanine transferase (ALT); although unchanged in the SH groups; were increased in the rats treated with PH + C + Cy; and were greater than after PH only. However LW / BW ratios increased after PH but had returned to preoperative levels by 2 weeks. The changes in LW / BW ratio were not modified by the cytosol or cyclosporine

Restoration of liver mass after partial hepatectomy - implications for living donor liver transplantation : transplantation

In living donor liver transplantation; the recipient liver undergoes more rapid regeneration than the remnant liver in the donor. In this study we investigated the factors which may be responsible for the difference in the regenerative response between the donor and the recipient. Long Evans rats were subjected to either partial hepatectomy (PH) or sham operation (SH) and were treated with liver cytosol (C) and cyclosporine (Cy). The rats were sacrificed at 24; 48; 72 and 96 hours and 1 and 2 weeks postoperatively. The livers were removed to determine the liver weight/body weight (LW / BW ) ratio and the mitotic index. The mitotic index; serum aspartate transferase (AST) and serum alanine transferase (ALT); although unchanged in the SH groups; were increased in the rats treated with PH + C + Cy; and were greater than after PH only. However LW / BW ratios increased after PH but had returned to preoperative levels by 2 weeks. The changes in LW / BW ratio were not modified by the cytosol or cyclosporine