Prevalence of osteoporosis and hypovitaminosis d at siriraj metabolic bone disease clinic / Prevalência de osteoporose e hipovitaminose d na siriraj metabolic bone disease clinic

ABSTRACT Objective: To identify the prevalence of osteoporosis and hypovitaminosis D among patients at the Siriraj Metabolic Bone Disease (MBD) Clinic, and to compare initial vitamin D levels in patients with and without a history of fragility fractures. Methods: Medical records of patients who attended our MBD clinic between 2012 and 2015 were retrospectively reviewed. Patient baseline demographic, clinical, bone mineral density (BMD), and laboratory data were collected and analyzed. Osteoporosis was diagnosed when patients had a BMD T-score <-2.5 or presented with fragility fractures. Results: There were 761 patients included in this study. Of these, 627 patients (82.4%) were diagnosed with osteoporosis and 508 patients (66.8%) had fragility fractures. Baseline serum 25-hydroxyvitamin D (25(OH)D) levels were available in 685 patients. Of these, 391 patients (57.1%) were diagnosed with hypovitaminosis D. When evaluated only in patients with fragility fractures, the average initial 25(OH)D level was 28.2±11.6 ng/mL, and the prevalence of hypovitaminosis D was 57.6%. Conclusion: A high prevalence of osteoporosis and hypovitaminosis D was found among patients at our clinic; two-thirds of patients had a history of fragility fractures, and no difference in initial 25(OH)D levels was seen between patients with and without fragility fractures. Level of Evidence III, Retrospective Study .

RESUMO Objetivo: Identificar a prevalência de osteoporose e hipovitaminose D entre os pacientes na Siriraj Metabolic Bone Disease (MBD) Clinic e comparar o nível inicial de vitamina D em pacientes com e sem história de fratura por fragilidade óssea. Métodos: Os prontuários de pacientes atendidos em nossa clínica MBD durante o período de 2012 a 2015 foram analisados retrospectivamente. Os dados demográficos, clínicos, densidade mineral óssea (DMO) e os dados laboratoriais basais foram coletados e analisados. A osteoporose foi diagnosticada quando os pacientes tinham DMO com escore T≤ -2,5 ou fraturas por fragilidade óssea. Resultados: Foram incluídos 761 pacientes dos quais, 627 pacientes (82,4%) foram diagnosticados com osteoporose e 508 (66,8%) tinham fraturas por fragilidade. O nível sérico basal de 25-hidroxivitamina D (25(OH)D) estava disponível para 685 pacientes. Desses, 391 pacientes (57,1%) foram diagnosticados com hipovitaminose D. Quando avaliado apenas em pacientes com fratura por fragilidade óssea, o nível inicial médio de 25(OH)D foi de 28,2 ± 11,6 ng/ml e a prevalência de hipovitaminose D foi de 57,6%. Conclusão: Encontrou-se alta prevalência de osteoporose e hipovitaminose D entre os pacientes de nossa clínica, sendo que dois terços deles tinham história de fratura por fragilidade óssea e nenhuma diferença no nível basal de 25(OH)D entre pacientes com e sem fratura por fragilidade. Nível de Evidência III, Estudo Retrospectivo

The accuracy of preoperative templating in total knee arthroplasty.

OBJECTIVE: Radiographic templates have been developed to assist with the preoperative planning process. However, the clinical usefulness of preoperative templating in total knee replacement is still lacking. The present study aims to evaluate the accuracy of preoperative templating in primary total knee replacement. MATERIAL AND METHOD: A retrospective study of 98 patients and 113 knees was carried out. Both the anteroposterior and lateral radiographic views were templated using the templates for DePuy Sigma PFC, fixed bearing total knee system and the template size was documented for each patient pre-operatively. The operative records were then reviewed to determine the size of the implant used during the operation. RESULTS: The overall accuracy between the preoperative template size and the final implant size was 50.4% for the femoral component and 55.8% for the tibial component. The highest prediction for tibial assessment was the anteroposterior view and the lateral intercondylar view for femoral assessment. CONCLUSION: Approximately 50% of the patients had a preoperative template size that matched the actual implant used. Many factors influence the final choice of the prosthesis used during total knee replacement; therefore, the preoperative template size can only be used as a rough guide.

Neuropathic arthropathy of the elbow: a report of two cases.

BACKGROUND: Neuropathic arthropathy (charcot joint) of the elbow is a rare condition. It is among the least frequently reported charcot pathology of the joint. The clinical symptoms are characterized by a painless and unstable joint. Infection in the neuropathic joint is rare. Only a limited number of cases have been reported in the literature. The authors present two cases of neuropathic arthropathy of the elbow. One of them was diagnosed as Septic neuropathic arthropathy. MATERIAL AND METHOD: Two patients with neuropathic arthropathy of the elbow (an infected and a noninfected case) were treated at our department. Both patients were over 60 years old. The underlying conditions associated with the arthropathy included combined median and ulnar neuropathy in the infected case and idiopathic in the non-infected case. Both of the patients had a history of specific trauma at the affected elbows. The radiographs of the elbows revealed dislocation, fracture fragmentation and some bony sclerosis. The management in the non-infected case aimed to maintain the function of the elbow with a short period of immobilization and physical therapy. For the infected case, the patient was treated successfully with systemic antibiotic, surgical debridement and a period of immobilization with an external fixator RESULTS: The patients were followed-up for approximately 9 months for the non-infected and 2 years for the infected case. Both of them had painless and functional range of motion of the elbows in the most recent follow-up examination. For the infected case, the surgical incision healed well and there was no recurrent discharge from that affected elbow. CONCLUSION: In the first case, with neuropathic arthropathy of the elbow, the investigations were made to find the underlying disease. The second case with septic neuropathic joint, systemic antibiotic, surgical debridement and appropriate immobilization were needed. With gross instability and marked distortion of the joint, the elbow of both patients functioned remarkably well.