RESUMEN
Serum samples from 465 subjects aged between 1 and 25 years were tested for antibody against hepatitis A virus (HAV) [anti-HAV IgG and IgM] to determine the seroprevalence of HAV antibody and do a cost-benefit analysis for decision making about vaccination against HAV among the general population of Bangladesh. A high prevalence of anti-HAV (74.8%) was observed in the study population; the whole study population was found positive for anti-HAV by the age of 25 years. On performing the cost-benefit analysis, it was found that the cost for vaccination with screening for anti-HAV was almost three times cheaper than vaccination without screening. Thus, in the present socioeconomic condition of Bangladesh, a policy based on screening for HAV antibody before vaccination is recommended.
Asunto(s)
Adolescente , Adulto , Bangladesh/epidemiología , Niño , Preescolar , Control de Enfermedades Transmisibles/métodos , Análisis Costo-Beneficio , Femenino , Hepatitis A/epidemiología , Anticuerpos de Hepatitis A/sangre , Vacunas contra la Hepatitis A/administración & dosificación , Virus de la Hepatitis A/inmunología , Humanos , Inmunoglobulina G/sangre , Inmunoglobulina M/sangre , Lactante , Masculino , Tamizaje Masivo , Estudios Seroepidemiológicos , Adulto JovenRESUMEN
Traumatic ventricular septal defect (VSD) is a very uncommon condition, especially in association with blunt chest trauma. A healthy young adult was diagnosed as a case of VSD one week after a road-traffic accident. History and other medical records suggest it was an acquired post-traumatic VSD. Thus, all patients of blunt chest trauma deserve close cardiac evaluation.