RESUMEN
Background: Globally, the Case Fatality Rate (CFR) due CoVID19 ranges from 0.1-4.7%. CoVID-19 death remained 0.5% till April 2021 in Assam as compared to India (1.3%). Though pre-existing diseases greatly contributes to CFR yet its association study from India is scarce. This study documents association of such death with comorbidities in a tertiary hospital of Assam. Methods: Retrospective analysis of 234 COVID death from May 2020 to December 2020 in Jorhat Medical College (JMCH) were done. Demography, comorbidities at admission and blood parameters were analyzed in Epi-Info version7.2.4.0. Continuous variables were presented as mean±SD or median (interquartile ranges) and correlated with death. Results: Out of 3781 confirmed cases admitted in JMCH, 234 died (72% male) with CFR of 0.06. Highest deaths occurred between 61 to 70 years. Median duration of disease was 4 days (IQR 2-8days). Acute respiratory distress or pneumonia was most common (53.1%) symptom followed by septicemia (24.6%) at admission. Diabetes mellitus (36.6%), hypertension (24.8%), diabetes with hypertension (11.4%) and chronic kidney diseases (22.4%) were common chronic comorbidities. About 64% cases had thrombocytopenia, and 66.9% had leukocytosis at admission. Many cases had coronary artery diseases, left ventricular failure, post-operative complications, post-partum complications, severe hemoptysis, severe anemia, metabolic encephalopathy, acute myocardial infarction, non-ketotic coma and acute gastroenteritis and SARS-COV2 infection. Conclusions: CoVID19 associated mortality in Assam was low and mostly among elderly with chronic comorbidities. CKD was most significantly associated with mortality. Superimposed bacterial infection at admission contributed to many fatal outcomes in COVID19, thus warranting proper empirical antibiotic.