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Background: The increasing prevalence of diabetes mellitus Worldwide and its complex nature of predisposing one to different ailments like obesity, eye defect, cardiovascular diseases etc. calls for alternative measures in the management of the disease. Muskmelon (Cucumis melo L.) is an underutilized food with a lot of nutritional and medical potential which are used traditionally in the management of different ailments like diabetes mellitus. Objective: The aim of this study was to evaluate the anti-diabetes and anti-lipidemic effects of muskmelon fruits and seeds in streptozotocin induced-diabetic rats. Methods: Diabetes was induced using intravenous Streptozotocin at a dose of 42 mg/kg of body weight into the tail veins to groups 2-5. Twenty-five male albino rats were divided into 5 groups, group 1 normal control, group 2- diabetic control, group 3- Glucophage treatment, group 4-500mg/kg BW muskmelon fruits extract, and group 5- 500mg/kg bw muskmelon seeds extract and were treated for 2 weeks. Fasting blood glucose, body weight, triglyceride, LDL, HDL and total cholesterol were evaluated. Results: The result shows that the extract caused a significant increase in the body weight, HDL-cholesterol, and a significant decrease in triglyceride, LDL-cholesterol, total cholesterol, and fasting blood glucose. Although the extract performed well there is a significant difference between the group that took Glucophage and the groups that ate muskmelon fruits and seed extract p<0.05 Conclusion: The result proved the anti-diabetic and anti-lipidemic effect of muskmelon fruits and seeds which could be added to the pool of other food used in the management of diabetes mellitus which will lead to diet diversification.
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The aim of this study was to evaluate the nutritional and health implication of Pterocarpus santalinoides (Uturukpa) and Napoleona imperialis (Mkpodu) leaves. The vegetables were harvested from the forest in Udi Local Government area in Enugu State and identified at Department of Agronomy, Enugu State University of Science and Technology, Enugu, Nigeria. The vegetables were trimmed and washed with deionized water and drained. The vegetables were ground using hammer mill into paste separately and coded as sample A (Pterocarpus santalinoides) and sample B (Napoleona imperialis). Both samples were analyzed in the laboratory for proximate, vitamins, minerals, anti-nutrients and phytochemicals. The results were analyzed statistically using mean and standard deviation. The result showed that the proximate composition (on wet wt. basis) of sample A and B were protein 1.06 and 5.27%, fat 0.98 and 0.71%, fibre 0.90 and 1.01%, ash 2.73 and 1.27% and carbohydrate 30.63 and 23.54% respectively. The vitamin constituents were beta carotene 360.00 and 360.00 µg/100 g, vitamin C 5.20 and 7.13 mg/100 g and vitamin E 2.80 and 1.45 mg/100 g for sample A and B respectively. The result of the minerals were iron 3.49 and 1.40 mg/100 g, zinc 0.92 and 2.10 mg/100 g, calcium 36.00 and 25.60 mg/100 g, magnesium 20.01 and 25.20 mg/100 g and potassium 11.27 and 70.92 mg/100 g for sample A and B respectively. The result of the pyhtochemicals revealed that both leaves contained an appreciable amount of phytochemicals which are component of herbs use for ethnomedicine. The anti-nutrients in sample A and B were cyanide 0.48 and 0.94%, oxalate 1.08 and 3.87% and phytate 0.25 and 6.01% respectively. The high protein, fibre and mineral content of Napoleona imperialis is of interest, hence these lesser known vegetables are recommended due to its high nutritional content and health benefit.
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Background/Objective: Processing improves the nutritional quality of food and may/not lead to nutrient losses. Processing is done to eliminate inactive microorganisms/ antinutrients and extend the shelf life of food. Moringa oleifera plant is an important tree in some part of Nigeria having been successfully used as food, medicinal and for industrial purpose. This study was designed to determine the effect of processing on the nutritional profile of Moringa olifrera leaves and seeds. Materials and Methods: The leaves and seeds were harvested from the forest. The leaves were washed, drained and divided into three portions. The first portion was processed raw, the sun and shade dried samples were the second and third portion. The seeds were cracked and divided into six portions. The first portion was processed raw and the other five portions were fermented for 24, 48, 72, 96 and 120 h respectively. The samples were analyzed for proximate, vitamin, mineral, and anti-nutrients contents using the standard method. Results: The proximate composition of the seeds showed that the samples had a range of moisture, 16.63-17.75%, protein 13.92-38.45%, fat 14.93-19.00%, fibre 3.94-7.10%, ash 1.96-6.22% and carbohydrate 9.08-36.61%/100 g respectively. The ranges for the mineral contents of the seeds were iron 2.10-33.35 mg, zinc 1.19-1.35 mg/100 g, and iodine 12.33-126.61 mg. Also, the ascorbic acid content of the seeds ranged from 3.57- 24.55 mg. The anti-nutrient contents of the seeds were 0.03 – 1.35/100 g saponin, 0.21 – 6.25 mg/100 g of oxalate, 0.11 – 0.28 mg tannins and 5.69 – 16.81 mg/100 g of phytate. The proximate composition of the vegetables ranged from 8.99 – 75.33% moisture, 6.01 – 17.78% protein, 0.64 – 3.89% fat, 3.14 – 11.96% fibre, 2.46 – 15.22% ash and 12.01 – 48.52% carbohydrate. The ranges for mineral contents of the vegetables were iron 0.04 – 0.23 mg, zinc 0.03 – 0.10 mg and iodine 13.66 – 46.61 mg. The vitamin levels of the vegetables were ascorbic acid 56.43 – 167.66 mg/100 g. The level of the anti-nutrients in the vegetables ranged from 0.04 – 1.26 mg/100 g saponin, 0.31 – 8.44 mg/100 g oxalate, 0.05 – 0.20 mg/100 g tannins while phytate varied from 3.31 – 13.20 mg/100 g. Conclusion: Processing of both leaves and seeds of Moringa olifera increased their nutrient density and reduced the concentration of anti-nutrients. The consumption of Moringa olifera should be popularized to diversify diet and extend their food use.