RESUMEN
Although stress will cause dynamic and stimulus in life, special amount of stress is beneficial for human being, but too much of it may case physical and psychological illness. Study the effect of Quran reading instruction on stress reduction in the form of comparison of experimental and control groups and determine the role of gender and group factors on global scores of stress. This study was quasi-experimental and after cluster sampling, 170 person of 16- 26 year old which consisted of 87 Quran instruction classes attendants and 83 of control group, were tested with SS1 questionnaire, before and after instruction. There was significant difference between two groups in the four subscales of stress [Wilks' Lambda = 0/992, F[4, 163] = 3/47, P<0/01, eta[2] = 0/078], there was not meaningful difference between men and women in the four subscales of stress [Wilks' Lambda - 0/991, F[4, 163] - 0/380, P<0/823, eta[2] - 0/009] there was not significant interaction between membership in group and gender [F[l, 166] = 0/318, P<0/574, eta[2]= 0/002]. In comparison with control group, in experimental group Quran instruction has reduced stress in significant level. There was not significant difference between men and women in the four subscales of stress. There was not significant interaction between membership in group and gender