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Genet. mol. biol ; 26(3): 235-240, 2003. ilus, tab
Artículo en Inglés | LILACS | ID: lil-346309

RESUMEN

The allele frequency distributions of three VNTR (D1S80, APOB and D4S43) and three STR (vW1, F13A1 and DYS19) loci were investigated in two Afro-Brazilian populations from the Amazon: Curiau and Pacoval. Exact tests for population differentiation revealed significant differences in allele frequency between populations only for the D1S80 and APOB loci. A statistically significant deviation from the Hardy-Weinberg equilibrium was observed only in the D1S80 locus of the Pacoval sample. A neighbor-joining tree was constructed based on DA genetic distances of allele frequencies in four Afro-Brazilian populations from the Amazon (Pacoval, Curiau, Trombetas, and Cametá), along with those from Congo, Cameroon, Brazilian Amerindians, and Europeans. This analysis revealed the usefulness of these Amp-FLPs for population studies - African and African-derived populations were closely grouped, and clearly separated from Amerindians and Europeans. Estimates of admixture components based on the gene identity method revealed the prevalence of the African component in both populations studied, amounting to 51 percent in Pacoval, and to 43 percent in Curiau. The Amerindian component was also important in both populations (37 percent in Pacoval, and 24 percent in Curiau). The European component reached 33 percent in Curiau


Asunto(s)
Humanos , Masculino , Femenino , Niño , Adolescente , Adulto , Persona de Mediana Edad , Población Negra , Frecuencia de los Genes , Marcadores Genéticos , Repeticiones de Minisatélite , Polimorfismo Genético , Brasil , Genética de Población
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