Antimicrobial resistance; comparison of Escherichia coli in different areas of Lahore

Since the development of antibiotics there is a growing concern about the increasing incidence of antibiotic resistance. As a result the therapeutic value of originally effective antibiotics become significantly reduced overtimes. Extensive data is available on antibiotic susceptibilities of hospital isolates but very little information is available about the susceptibilities of community strains. Descriptive. July 2004 to June 2005. Department of Microbiology, Shaikh Zayed Hospital Lahore. Hence the present study was design to assess the environmental load of the antibiotic resistance using fecal flora as an indicator of overall problem. It will also provide guidance in antibiotic protocol for antibiotic policy. Objective of the present study was to determine the developing resistance to beta - Lactam Antibiotics which is the commensal microbe of enteric tract. One hundred samples were collected from ten different areas of Lahore city [10 samples from each area] and were inoculated on Mac Conkey's agar. Five morphologically distinct lactose fermenting colonies were selected and identified using standard laboratory methods. Five hundred different colonies of E.coli were identified and analyzed for their susceptibility to b-lactam antibiotic. Out of 500 isolates, the resistant isolates with ampicillin [48%], coamoxiclav [40%] and cephradine [37%] were detected, with cheaper oral agents high prevalence of resistance was detected. Ampicillin, co-amoxiclav and cephradine are not much useful for the treatment of urinary tract infection and septicemia caused by E-coli and other Members of fecal flora

Comparison of Ponsetitechnique with Turco's posteromedial release in the management of congenital talipes equinovarus

To compare the results of Ponseti technique with one stage Turco's posteromedial release for correction of clubfoot in children of less than 12 month of age Comparative study Department of Orthopedics and Spine Surgery Postgraduate Medical Institute, Hayatabad Medical Complex Peshawar, from October 2008 September 2010. Patients were randomly selected by drawing lots, with even number included in group A [Ponseti Technique] and odd number in group B [Turco's posteromedial release]. Patients of either sex with age less one year having congenital talipes equinovarus were evaluated preoperatively by Pirani score, postoperatively by Mac Key score and were followed up for 2 years. Out of sixty patients, 23[38.3%] were males and 37 [61.7%] females. Fourteen [23.3%] patients had bilateral while 46 [76.7%] had unilateral deformity. Minimum age was 2 week, maximum 52 week and average 5.58 week. Using Pirani score preoperatively, there were 36[60%] patients with severe abnormality and 24[40%] feet were moderately abnormal. Using Mac Key score the functional results at last follow up in Group A were excellent in 16[26.7%], good in 13[21.7%] and failure noted in 1[1.7%] patient. At last follow up, functional results in Group B were excellent in 14[23.3%], good in 10[16.7%], fair in 4[6.7%] and poor in 1[1.7%] patient. Ponseti technique for an idiopathic clubfoot should be the choice for clubfeet. When there is recurrent deformity or resistant club foot then operative treatments may be considered