Antifungal activity of cheilanthes grisea blanford.

Cheilanthes grisea Blanford, a rare fern of Kumaun hills, is a member of psinopteridaceae family of leptosporangiate group of ferns. Aq. methanolic extract (50%) of this fern was screened for antifungal activity by thin layer autobiochromatographic methods. Chemical investigation of the fern fronds of C. grisea Blanford revealed the presence of a flavonol glycoside, quercetin-3-O-β-glycosyl (1→2) rhamnoside from an antifungal active fraction of n-butanol soluble of aqueous ethanolic extract. Its structure was elucidated by UV, 1HNMR, and hydrolytic methods.