RESUMEN
The present tests, in male Wistar rsts, center around the trophic and functional changes of the pancreatic gland (R G), both exocrine and endocrine, induced by different types of autonomic nervous interruptions. First Group of Tests: Following one year celiac ganglionectomy (CG), nonpancreatectomized (Non-Pt) rats showed, basally, in blood, adrop of glucose (G), without changes of insulin (I). At autpsy, the CG animals showed an increase of the pancreatic we weight, of the total protein, of the RNA but not DNA. In the Pt. 95 per cent rats, superimposing CG triggered, on the one hand, a drop to control values of the raised G blood levels, and on the other, a rise of I Besides, in feces, a rising of chymotrypsin concentration. At autopsy, in the PG, an increase of total protein and of RNA. Second Group of Tests: CG, after 6 months, induced, in blood, both basally and a 2 h glucose tolerance test, significant opposite enzyme activities changes in respect to C. Indeed, as amylase (A) was increased, that of lipase (L) was depressed. When alcohol feeding (AF) was superimposed to CG rats, a reversal of the L values was observed. The latter reached levels significantly higher those of the C. In in-vitro tests, the isolated islets of CG disclosed to release more I to the bath medium than those of the C animals. Third Group of Tests: Analyzing, in conscious animal, the L excretory changes in the basal bile pancreatic secretion (BB-PS) induced by chronic (2 months interruption of the autonomic nervous innervation of the PG, it was found that CG, truncal vagotomy (V), the association of CG + V, peri-Vaterian duodenotomy (PV-D), but not bilateral splachnicectomy (Spl), inhibit, significantly the L output. It was also shown that superimosing AF to the V or CG + V animals reverted to C values the I depressed levels...
Asunto(s)
Animales , Masculino , Ratas , Sistema Nervioso Autónomo/fisiología , Ganglionectomía , Páncreas/cirugía , Regeneración , Sistema Nervioso Autónomo/cirugía , Plexo Celíaco/fisiología , Plexo Celíaco/cirugía , Etanol/toxicidad , Insulina/metabolismo , Islotes Pancreáticos/metabolismo , Lipasa/metabolismo , Páncreas/inervación , Páncreas/metabolismo , Pancreatectomía , Ratas Wistar , VagotomíaRESUMEN
A proposito de la incidencia creciente del cancer de la via biliar extrahepatica se revisan las caracteristicas clinicopatologicas, el tratamiento y el pronostico de este particular tumor en base a los datos obtenidos de la serie de pacientes de los autores y a las referidas en la bibliografia
Asunto(s)
Adulto , Persona de Mediana Edad , Humanos , Masculino , Femenino , Adenocarcinoma , Neoplasias de los Conductos BiliaresRESUMEN
Se analiza la experiencia clinica sobre 64 casos de pancreatitis aguda, asistidos por grupo de cirujanos del Hosptipal Dr. Bernardo Houssay, completada por una serie practicamente paralela del Hospital Aleman presentada por el relator
Asunto(s)
Adulto , Persona de Mediana Edad , Humanos , Masculino , Femenino , PancreatitisRESUMEN
A proposito de la incidencia creciente del cancer de la via biliar extrahepatica se revisan las caracteristicas clinicopatologicas, el tratamiento y el pronostico de este particular tumor en base a los datos obtenidos de la serie de pacientes de los autores y a las referidas en la bibliografia