RESUMEN
<p><b>OBJECTIVE</b>To observe the therapeutic effect of Yishen Jianpi Huayu Decoction (YJHD) in treating chronic renal insufficiency (CRI).</p><p><b>METHODS</b>Forty-three patients with CRI were selected and randomly assigned into two groups, the 24 patients orally administered with YJHD in the treated group and the 19 administered with coated aldehyde oxystarch in the control group, the therapeutic course was 2 months. The symptom, physical sign, kidney function, blood lipids of patients were observed before and after treatment and the comprehensive clinical efficacy of the treatment was evaluated.</p><p><b>RESULTS</b>The total effective rate was 87.5% and 52.6% in the two groups respectively, it was significantly higher in the treated group than that in the control group (P < 0.05). The improvement of kidney function, blood lipids, and hemorrheologic parameters in the treated group were superior to those in the control group (P < 0.05).</p><p><b>CONCLUSION</b>YJHD is effective in treating chronic renal insufficiency.</p>