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Journal of Zhejiang University. Medical sciences ; (6): 361-364, 2004.
Artículo en Chino | WPRIM | ID: wpr-353304

RESUMEN

<p><b>OBJECTIVE</b>To investigate the effects of calcium on learning and memory ability of rats exposed to low level lead before and after birth.</p><p><b>METHODS</b>Wistar dam rats were randomly divided into normal group, lead-contaminated group and lead with Ca group. Corresponding food and water were given to pregnant rats from d 15 of gestation and to young rats till 7 w after birth. The weight of brain and hippocampus, blood lead content, serum calcium content, learning and memory ability of young rats were tested.</p><p><b>RESULT</b>The blood lead concentrations: lead-contaminated group was the highest, lead with Ca group the second and normal group the lowest. Serum calcium concentrations: normal group and lead with Ca group were both higher than lead contaminated group. Ability of learning and memory: lead with Ca group was better than lead-contaminated group, but poorer than normal group. No differences were found upon the weight of brain and hippocampus in all groups.</p><p><b>CONCLUSION</b>A minilaparotomy approach for curative resection of rectal cancer may be an ideal alternative approach to conventional laparotomy.</p>


Asunto(s)
Animales , Femenino , Masculino , Ratas , Calcio , Farmacología , Feto , Hipocampo , Patología , Plomo , Sangre , Toxicidad , Aprendizaje , Memoria , Ratas Wistar
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