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Chinese Journal of Pathophysiology ; (12): 1471-1477, 2016.
Artículo en Chino | WPRIM | ID: wpr-495870

RESUMEN

Cardiovascular diseases are closely related to proliferation , injury and apoptosis of the cells in the cardiovascular system .For instance , endothelial cells play an important role in the pathogenic process of hypertension and atherosclerosis , and smooth muscle cells and monocytes/macrophages involve in the formation of atherosclerotic plaque . Recently, it has been confirmed that long noncoding RNA (lncRNA) regulates proliferation, apoptosis, injury, autophagy and differentiation of the cells by a series of regulatory mechanisms , thus participating in the development and progression of cardiovascular diseases .This article is to review the recent research progress on the function of lncRNAs and their regu -latory roles in the cardiovascular diseases at cellular and molecular levels .

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