Effects of cigarette smoking on hypoxic pulmonary vasoconstriction in piglets—role of sympathetic nerve, histamine,prostaglandins and leukotrienes / 中国病理生理杂志

In order to investigate the effects of cigarette smoking on hypoxic pulmonary vasoconstriction(HPV) in piglets, receptor or synthetic enzyme blockers of sympathetic nerve, histamine, prostaglandins(PGs) and leukotrienes(LTs) were used. Results showed that hypoxia increased PVR by adrenergic alpha receptor, LTs and PGs to 72.5%(3min. P