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Annals of Saudi Medicine. 2012; 32 (2): 121-126
en Inglés | IMEMR | ID: emr-118089

RESUMEN

It has been proposed that glutamate decarboxylase 2 and the dopamine D2 receptor are involved in the brain reward cascade to increase carbohydrate craving and cause eating disorders. We investigated the association between the polymorphisms of the CAD2 and DRD2 genes and obesity with a higher body mass index [BMI] in Taiwanese patients. A retrospective, case-control study at Antai Tian-Sheng Memorial Hospital from 1 January to 31 December 2009. Of 300 subjects enrolled in the study, 132 were obese [BMI>30 kg/m[2]] and 168 controls were not obese [BMI

Asunto(s)
Humanos , Masculino , Femenino , Adulto , Persona de Mediana Edad , Polimorfismo Genético , Receptores de Dopamina D2/genética , Glutamato Descarboxilasa/genética , Índice de Masa Corporal , Predisposición Genética a la Enfermedad , Estudios Retrospectivos , Estudios de Casos y Controles
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