Aneurismas experimentales en conejos por angioplastia con balón / Experimental aneurysms in rabbits by ballon angioplasty

Objetive. To perform a new model of experimental aneurysms in rabbits and to achieve a training in basic endovascular techniques. Material and method. We introduce a new aneurysm model in rabbits. First we performed a balloon angioplasty in the right carotid artery in the neck, then three weeks later we carry out an angiography with a diagnostic catheter from the right femoral artery to check aneurysm patency. Results. We were able to perform 10 aneurysms in ten rabbits; they were patent three weeks after their creation. The aneurysmscreation and the angiography performed to evaluate the aneurysm patency required a similar skill necessary to perform basic endovascular interventions. Conclusion. Aneurysms created from balloon angioplasty in the carotid artery in rabbits are a suitable model at least in the short term. The process of aneurysm formation and its study is an useful training in basic endovascular techniques.

Aneurismas experimentales en ratas / Experimental aneurysms in rats

Objective. 1. The creation of an aneurysm model in an arterial bifurcation for microsurgical training in rats. 2. To verify angiographically the aneurysms patency performing endovascular maneuvers. Material and method. 10 Wistar rats weighted 400-600g were used. Ten aneurysms were performed, 9 in the final aortic bifurcation and one in the origin of the renal artery. The aneurismal sac derived from the external iliac vein. Angiography in each animal was done to examine aneurysm patency. At the same time we tried to manipulate microcateter and microguidewire in the aortic lumen. After that the aneurysm was microscopically inspected in order to verify the angiographic findings. Results. The aneurysms and the angiographic study could be performed in every animal. Four aortic and the renal artery aneurysms were not visualized in the angiography (totally thrombosed). The other five were partially thrombosed. Under microscopic aneurismal inspection could be found thrombus into the sac. The endovascular navigation was difficult due to the animal size. Conclusion. The bifurcation aneurysm model is a good microsurgical training. In our hands the aneurysms created had a high rate of spontaneous thrombosis. Because of animal size it is not a good model for endovascular training.