Characteristics of Polypoidal Choroidal Vasculopathy Associated with Subretinal Hemorrhage

PURPOSE: To evaluate the clinical features and risk factors of hemorrhagic complications in polypoidal choroidal vasculopathy (PCV) using spectral domain-optical coherence tomography (SD-OCT) and indocyanine green angiography (ICGA). METHODS: We respectively reviewed the data from 43 patients (45 eyes) diagnosed with PCV who received ICGA between January 2010 and October 2013. The patients were divided into 2 groups: 16 patients (17 eyes) with subretinal hemorrhage (subretinal hemorrhagic PCV group) and 27 patients (28 eyes) without subretinal hemorrhage (control group). Based on the ICGA and SD-OCT findings, the number, morphology, location, size of polyps, pigment epithelial detachment (PED), and serous retinal detachment (SRD) were measured and compared between the 2 groups. We also analyzed systemic diseases and history of antithrombotic agents associated with subretinal hemorrhage in PCV. RESULTS: The size of polyps measured by ICGA was significantly different between the 2 groups (p = 0.006). As the size of polyps increased, the size of subretinal hemorrhage, height of PED, base diameter and height of SRD increased (p 0.05). CONCLUSIONS: The patients in the subretinal hemorrhagic PCV group had larger-sized polyps than the patients in the control group. This result suggests that eyes with larger-sized polyps are at risk for hemorrhagic complications and require more careful follow-up and observation in PCV treatment-naive patients.

Characteristics of Polypoidal Choroidal Vasculopathy Associated with Subretinal Hemorrhage

PURPOSE: To evaluate the clinical features and risk factors of hemorrhagic complications in polypoidal choroidal vasculopathy (PCV) using spectral domain-optical coherence tomography (SD-OCT) and indocyanine green angiography (ICGA). METHODS: We respectively reviewed the data from 43 patients (45 eyes) diagnosed with PCV who received ICGA between January 2010 and October 2013. The patients were divided into 2 groups: 16 patients (17 eyes) with subretinal hemorrhage (subretinal hemorrhagic PCV group) and 27 patients (28 eyes) without subretinal hemorrhage (control group). Based on the ICGA and SD-OCT findings, the number, morphology, location, size of polyps, pigment epithelial detachment (PED), and serous retinal detachment (SRD) were measured and compared between the 2 groups. We also analyzed systemic diseases and history of antithrombotic agents associated with subretinal hemorrhage in PCV. RESULTS: The size of polyps measured by ICGA was significantly different between the 2 groups (p = 0.006). As the size of polyps increased, the size of subretinal hemorrhage, height of PED, base diameter and height of SRD increased (p 0.05). CONCLUSIONS: The patients in the subretinal hemorrhagic PCV group had larger-sized polyps than the patients in the control group. This result suggests that eyes with larger-sized polyps are at risk for hemorrhagic complications and require more careful follow-up and observation in PCV treatment-naive patients.

A Case of Optic Disc Hemorrhage Associated with Buried Optic Nerve Head Drusen

PURPOSE: We report a case of optic disc hemorrhage associated with buried optic nerve head drusen in a pediatric patient. CASE SUMMARY: A 10-year-old female visited our clinic with a floating sensation in her left eye, 2 days in duration. Best corrected visual acuity was 1.0 in both eyes. Intraocular pressure, light reflex, relative afferent pupillary defect and color vision were normal. The patient showed a small optic disc with blurred, irregular margins in both eyes, and optic disc hemorrhage in the left eye on fundus examination. Visual field examination revealed an enlarged blind spot in the left eye. To achieve correct diagnosis, brain MRI was performed and revealed normal findings. On spectral-domain optical coherence tomography (OCT), hyper-reflective and heterogeneous mass like lesions were found with buried optic nerve head drusen. CONCLUSIONS: In general, optic nerve head drusen, has a good prognosis; however, visual field defects or hemorrhagic complications can occur, therefore, correct diagnosis and regular follow-up are necessary.