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Abstract Objective This study aims to perform a meta-analysis to figure out the efficacy of OK-432 sclerotherapy between Macrocystic (MAC) lymphangiomas and Microcystic (MIC) lymphangiomas. Methods We conducted a systematic review and meta-analysis to clarify the relationship between OK-432 and lymphangiomas. PubMed and ISI Web of Science were searched from inception to May 2022. Joanna Briggs Institute (JBI) manual was used to evaluate the risk of bias. We calculated pooled Relative Risks (RR) and 95% Confidence Interval (95% CI) using random effects model to evaluate the relations between OK-432 and lymphangiomas. Results A total of 11 studies (including 352 cases) about OK-432 sclerotherapy for lymphangioma were included in the current meta-analyses. The results suggested that the efficacy of OK-432 was significantly in MAC lesions than in MIC (RR = 1.51, 95% CI 1.298-1.764), with significant moderate degrees of heterogeneity among 11 studies (I2 = 51.2%, p = 0.025). Subgroup analyses suggested that there was significant association in both retrospective studies (RR = 1.26, 95% CI 1.03-1.53) and classification (by 1 cm) (RR = 1.37, 95% CI 1.04-1.80) were associated with the efficacy of OK-432. Conclusion To our knowledge, our study represents the first meta-analysis examining the efficacy of OK-432 in the treatment of different types of LMs. However, the regional differences and the age differences of the subjects are the main limitations of this study and should be avoided in further research. Our results suggested that OK-432 sclerotherapy for macrocystic lymphangiomas was more effective.
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Objective@#To explore the prevalence and trend of premature delivery in Shaoxing Maternal and Child Health Care Hospital from 2007 to 2018, so as to provide evidence for prevention of premature birth and promotion of perinatal health care. @*Methods@#The data of live births in Shaoxing Maternal and Child Health Care Hospital from 2007 to 2018 were collected,and premature birth rate,proportion of premature infants in different gestational weeks,as well as the trend of gender ratio,asphyxia and birth weight with gestational weeks were analyzed.@*Results@#From 2007 to 2018,there were 10 506 premature infants born in Shaoxing Maternal and Child Health Care Hospital. The preterm birth rate increased year by year （P<0.05）,and the annual average was 9.09%. The rate of multiple premature birth was 57.80%,which was higher than that of single premature birth （7.26%,P<0.05）. There were 110 cases of extremely preterm birth （1.05%）,2 997 cases of early preterm birth （28.53%）,and 7 399 cases of mild preterm birth （70.43%）. The proportions of extremely and early preterm birth increased year by year （P<0.05）. The asphyxia rate of premature infants was 9.70% （1 019 cases）,which decreased with the increase of gestational weeks （P<0.05）. The birth weight of premature infants decreased with the increase of gestational weeks （P<0.05）. The ratio of male to female in preterm infants was 1.22∶1,which was higher than 1.10∶1 in term infants （P<0.05）.@*Conclusion@#From 2007 to 2018,the preterm birth rate of Shaoxing Maternal and Child Health Care Hospital increased year by year,especially in extremely and early preterm birth.
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Undifferentiated sarcoma (UNDS) of the soft tissue is an exceedingly rare disease. Its diagnosis depends mainly on molecular and immunohistochemical analyses to exclude other soft-tissue sarcomas. It is difficult to confirm a positive diagnosis by imaging pathological features because of their rarity and similarity with other conditions. Since 2013, only 13 cases of undifferentiated soft-tissue sarcoma, mostly diagnosed through imaging of solid tumors in infant and children, have been reported. The authors present a rare case of a 3-month-old Chinese boy with UNDS primarily in the left lower extremity and characterized by a cystic and solid growth pattern