RESUMEN
Epimedii folium is a commonly used Traditional Chinese Medicine (TCM) for warming the kidney and strengthening the yang qi. It has androgen-estrogen-like effect. It can not only directly act on sexual organs to regulate hormone levels, but also exert sex-hormone-like effect through hypothalamus-pituitary-gonadal axis. Its regulation of hormone levels is similar to that of plant hormones. At present, Epimedii folium is commonly used with other TCMs to treat diseases caused by sex-hormone deficiency, such as male spermatopenia, asthenospermia, benign prostatic hyperplasia, functional erectile dysfunction, female premature ovarian failure, perimenopausal syndrome, dysfunctional infertility during ovulation, hyperandrogenemia of PCOS patients, etc.
RESUMEN
Objective To analyze the composing principles of Astragali Radix in Drug Standard of Ministry of Public Health of the People’s Republic of China-TCM Prescription Preparation;To provide references for clinical application and research and development of new medicine. Methods Traditional Chinese Medicine Inheritance Support System (V2.0) was used to establish database. Data mining methods, such as association rules, improved mutual information method, were used to analyze the diseases, syndrome rules, and common composing combinations of prescriptions containing Astragali Radix. Results Through analysis on the 446 cases of prescriptions containing Astragali Radix, 16 core medicine combinations and 18 diseases were discovered. Then, based on the 18 diseases, insomnia, consumptive disease and vertigo were chosen to make comparative analysis, the medicine using regularity and compatibility features of Astragali Radix in different diseases were disclosed. Conclusion Herbal medicines used frequently in prescriptions containing Astragali Radix could tonify qi and nourish blood. The medicine using is relatively concentrated, and the composition is clear. The composing principles reflect the compatibility features of Astragali Radix in treating different diseases, which are in accordance with the clinical application of multiple-efficacy Chinese medicine.