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Acta Pharmaceutica Sinica ; (12): 101-105, 2014.
Artículo en Inglés | WPRIM | ID: wpr-297963

RESUMEN

The osmotic pressure of ammonium sulfate solutions has been measured by the well-established freezing point osmometry in dilute solutions and we recently reported air humidity osmometry in a much wider range of concentration. Air humidity osmometry cross-validated the theoretical calculations of osmotic pressure based on the Pitzer model at high concentrations by two one-sided test (TOST) of equivalence with multiple testing corrections, where no other experimental method could serve as a reference for comparison. Although more strict equivalence criteria were established between the measurements of freezing point osmometry and the calculations based on the Pitzer model at low concentration, air humidity osmometry is the only currently available osmometry applicable to high concentration, serves as an economic addition to standard osmometry.


Asunto(s)
Sulfato de Amonio , Química , Congelación , Humedad , Concentración Osmolar , Osmometria , Métodos , Presión Osmótica , Soluciones
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