Application of percutaneous endoscopic gastrostomy in three infants with chronic kidney disease / 中华肾脏病杂志

The paper summarizes the clinical and follow-up data of percutaneous endoscopic gastrostomy (PEG) in three infants with chronic kidney disease to explore the safety and reliability of using PEG to improve the growth and development, and nutritional status. During follow-up, the weight and height of case 1 and 3 were obviously improved. Case 2 was followed up for 3 months, due to dying of cardiac arrest, and the infant's height and weight were not significantly improved. Serum albumin and prealbumin improved in 3 cases after PEG. No PEG-related infection occurred in 3 infants.

Etiological analysis of 264 cases with chronic kidney disease stage 2 to 5 in children / 中华儿科杂志

<p><b>OBJECTIVE</b>To study and summarize the etiology of children patients with chronic kidney disease (CKD) stage 2 to 5 seen in Children's Hospital of Fudan University from Jan. 2004 to Dec. 2013.</p><p><b>METHOD</b>By complying with the NKF-K/DOQI guidelines, we collected data of 264 cases of children patients with CKD stage 2-5 from Jan. 2004 to Dec. 2013 in the medical record system of Children's Hospital of Fudan University. And we retrospectively analyzed their age and CKD stage at first diagnosis, primary diseases, complications, etc.</p><p><b>RESULT</b>In the collected 264 cases, 52 cases (19.7%) were diagnosed at stage 2, 67 (25.4%) at stage 3, 52 (19.7%) at stage 4 and 93 (35.2%) at stage 5. For disease causes, 116 cases (43.9%) had congenital anomalies of the kidney and urinary tract (CAKUT), 61 cases (23.1%) had glomerular disease, 15 (5.7%) had hereditary kidney disease, 14 (5.3%) had other diseases and in 58 cases (22.0%) the causes of disease were unknown. In the group with age between 0 and 3.0 and 3.1 and 6.0 years, 57.1% (24 cases) and 60.0% (30 cases) had primary disease with CAKUT. In the group with age older than 10 years, 49.2% (30 cases) had primary disease with glomerular disease and 32.0% (32 cases) with unknown causes.</p><p><b>CONCLUSION</b>The major cause of CKD stage 2-5 in children in our hospital during the last ten years was CAKUT (43.9%), followed by glomerular disease (23.1%). The primary diseases of CKD were significantly different between the 2 age groups. CAKUT was more common in infants and preschool children while for adolescents, glomerular disease was the major cause.</p>

Three-dimensional finite element analysis of canine distalization through reducing resistance and distraction osteogenesis / 中国组织工程研究

BACKGROUND:Peridental membrane distraction osteogenesis exerts the functions at peridental membrane and leads to tooth movement. Alveolar bone distraction osteogenesis produces tooth movement through the displacement of the whole bone plate. OBJECTIVE:To establish three-dimensional finite element model of upper and lower jaw of healthy adults under three different conditions, and to compare the stress distribution and distal movement of the models using three-dimensional finite element analysis method. METHODS:Model 1:three-dimensional finite element model of the canine under normal conditions using a variety of software;Model 2:three-dimensional finite element model of the canine after distracting osteggenesis of the periodontal ligament;Model 3, three-dimensional finite element model of the canine after reducing resistance and distracting osteggenesis of the alveolar bone. The force loadings were stimulated among these models. RESULTS AND CONCLUSION:The biggest displacements on those three models occurred in canine crown on 1/3, and the displacement quantity on canine was model 2>model 3>model 1. The biggest equivalent stress concentrated in distal alveolar crest, and the equivalent stress was model 2

Study on anti-coagulant property of radio frequency sputtering nano-sized TiO2 thin films / 生物医学工程学杂志

Nano-TiO2 thin films were prepared by Radio frequency (RF) sputtering on pyrolytic carbon substrates. The influences of sputtering power on the structure and the surface morphology of TiO2 thin films were investigated by X-ray diffraction (XRD), and by scanning electron microscopy (SEM). The results show that the TiO2 films change to anatase through the optimum of sputtering power. The mean diameter of nano-particle is about 30 nm. The anti-coagulant property of TiO2 thin films was observed through platelet adhesion in vitro. The result of experiment reveals the amount of thrombus on the TiO2 thin films being much less than that on the pyrolytic carbon. It also indicates that the RF sputtering Nano-sized TiO2 thin films will be a new kind of promising materials applied to artificial heart valve and endovascular stent.