RESUMEN
This paper analyzes the current situation of innovation and entrepreneurship training mode of health information management specialty in medical colleges, expounds the basic ideas of innovation and entrepreneurship "ecosystem" construction in medical colleges, and discusses how to build "innovation and entrepreneurship platform of big data and artificial intelligence" as the center under the background of big data and artificial intelligence, with medical universities and their affiliated hospitals, medical related enterprises, and technology companies as the main body, and with entrepreneurial college, entrepreneurial laboratory, innovation studio, and entrepreneurial company as the organizational form of innovation and entrepreneurship talent training "ecosystem". In this "ecosystem", organizations gradually share interests, resources and development in different stages of students' growth.