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1.
Chinese Journal of Tissue Engineering Research ; (53): 8955-8960, 2013.
Artículo en Chino | WPRIM | ID: wpr-439738

RESUMEN

BACKGROUND:Ceramic-on-ceramic total hip arthroplasty can be applied to young patients requiring frequent activity and high quality of life. OBJECTIVE:To explore the short-term efficiency of ceramic-on-ceramic total hip arthroplasty in young and middle-aged patients of femoral neck fractures. METHODS:Fifty-one young and middle-aged patients under 50 years old with ceramic-on-ceramic total hip arthroplasty were selected to analyze the function of hip joints and the complication after operation. RESULTS AND CONCLUSION:Al the patients were fol owed up for 6 months to 44 months. At the last fol ow-up, the average Harris score was 92.0±3.4 points with an excellent and good rate of 94.1%. No dislocation was observed and three cases exhibited mild limping. Imaging examination showed that, no prosthesis loosing, broken, sinking or radiolucent line around prosthesis was observed. Ceramic-on-ceramic total hip arthroplasty in young patients with femoral neck fractures can effectively decrease the osteolysis, prosthesis loosing and sinking caused by the debris of wearing, prolong the working life of the prosthesis, and improve the patient’s quality of life.

2.
Chinese Journal of Tissue Engineering Research ; (53)2007.
Artículo en Chino | WPRIM | ID: wpr-594546

RESUMEN

108 patients with femoral neck fractures were treated with bipolar hemiarthroplasty in Qinhuangdao First Hospital from January 2002 to June 2008.All patients were followed up.The length of stay and operation,and the quantity of bleeding during operation were retrospectively analyzed;the results of X-ray before and after operation and the Harris hip scores after operation were assessed during follow-up to assess the clinical outcome.All patients were followed-up for 6 months to 5 years(average 3.4 years).According to the Harris hip score,42 cases rated as excellent,with mean score of 96.4;50 as good,with mean score of 85.7;10 as fair,with mean score of 74.5;6 as poor;the excellent and good rate was 85.2%.No prosthetic loosening or subsidence occurred according to X-ray results.Bipolar hemiarthroplasty for femoral neck fractures can reduce operation time,risk and blood loss during operation,and effectively improve quality of life,which is a satisfactory therapy for femoral neck fractures.

3.
Medical Journal of Chinese People's Liberation Army ; (12)2001.
Artículo en Chino | WPRIM | ID: wpr-564124

RESUMEN

Objective To prepare poriferous ?-tricalcium phosphate(?-TCP) particles and investigate the possibility of these particles to serve as bone graft and bone tissue engineering scaffold.Methods Poriferous anorganic bone particles were prepared with healthy bovine cancellous bone by removal of cells,defat and double calcination,finally with ?-TCP remained as the main ingredient.A bone defect was made in rabbit's femur,and it was repaired with poriferous ?-TCP bone graft.The results were observed by X-ray,molybdenum target films,fluorescence label and histology at the 4th,8th and 12th week after operation.Results The nature of cancellous bone structure was still maintained in the poriferous ?-TCP bone graft,even retaining its contour after it was transplanted in the bone defect.At the 4th week after operation,the graft was integrated with neighboring tissues,and the new bone gradually grew in the ?-TCP bone graft pores,with delineation of bone defect remaining clear.There was no obvious absorption of the graft,neither growth of soft tissues or bone tissue into the central part.At the 8th week after operation,the soft tissue further grew into the inside of the ?-TCP bone graft,and little bone tissue grew in the central part.At the 12th week after operation,the graft was firmly surrounded with new bone tissue,the demarcation between the graft and new bone becoming obscure,and the graft was partially absorbed,with thickening of bone trabeculae,which extended into the center of ?-TCP bone.However,the speed and quantity of the new bone formation were deteriorated.Histologic examination also found that the ?-TCP bone graft degenerated slowly with passage of time.Conclusion The poriferous ?-TCP bone graft possesses excellent osteogenesis for repairing a bone defect,and may be used as bone tissue engineering scaffold,though its degradation speed should be ameliorated.

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