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Acta Physiologica Sinica ; (6): 320-332, 2022.
Artículo en Chino | WPRIM | ID: wpr-927608

RESUMEN

Renal ischemia-reperfusion injury (IRI) is histologically characterized by tubular cell death. Diverse pathways of regulated cell death (RCD) have been reported to contribute to renal IRI in recent studies. In this review, we discuss the signaling pathways, regulators and crosstalk of RCD, including necroptosis, ferroptosis and pyroptosis, and their role in renal IRI in order to pave the way for new therapeutic opportunities.


Asunto(s)
Humanos , Apoptosis , Ferroptosis , Riñón/metabolismo , Necroptosis , Muerte Celular Regulada , Daño por Reperfusión/tratamiento farmacológico
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