Effect of bushen antai recipe and its various compositions on endometrial sexual hormones and receptors in mice with blastocyst implantation dysfunction / 中国中西医结合杂志

<p><b>OBJECTIVE</b>To compare the effects and mechanisms of Bushen Antai Recipe (BAR) and its different compositions, Bushen Recipe (BSR, the Shen-nourishing part) and Huoxue Recipe (HXR, the blood-activating part) on the endometrial receptivity in mice with blastocyst implantation dysfunction (BID).</p><p><b>METHODS</b>Model mice of BID induced by indomethacin were treated respectively with BAR, BSR and HXR from the first day of pregnancy, and killed on day 5 or 6. Samples of their serum and uterine were collected for detecting serum estradiol (E2), progesterone (P) contents using radioimmunoassay; and endometrial expression levels of their receptors, ER and PR, using immunohistochemistry.</p><p><b>RESULTS</b>Serum levels of E2 and P, and endometrial expression of ER and PR increased significantly on day 6 in mice after treated by BAR, but in those treated by BSR and HXR, the improvements were significantly lesser.</p><p><b>CONCLUSION</b>BAR, by combined application of both Shen-nourishing and blood-activating methods, could impact E2, P, ER and PR to improve the endometrial receptivity to a higher extent in BID mice so as to promote embryo implantation.</p>

Observation on therapeutic effect of acupuncture at Yanglingquan (GB 34) on sprain of external ankle joint / 中国针灸

<p><b>OBJECTIVE</b>To observe the increasing effect of Yanglingquan (GB 34) on sprain of external ankle joint.</p><p><b>METHODS</b>Seventy-nine cases of sprain of external ankle joint were semi-randomly divided into a treatment group (n = 46) and a control group (n = 33). The treatment group were treated with acupuncture at Yanglingquan (GB 34) and electro-magnetic therapy at local acupoints, and the control group with electro-magnetic therapy.</p><p><b>RESULTS</b>The cured rate and the total effective rate were 67.4% and 91.3% in the treatment group, and 36.4% and 69.7% in the control group, respectively, with a significant difference between the two groups (P<0.01, P<0.05).</p><p><b>CONCLUSION</b>Acupuncture at Yanglingquan (GB 34) has a better therapeutic effect on sprain of the external ankle joint.</p>