Two new dihydro-β-agarofuran sesquiterpenes from stems and leaves of Monimopetalum chinense / 中草药

Objective To study the chemical constituents from the stems and leaves of Monimopetalum chinense. Methods The constituents were isolated and purified by silica gel column chromatography and preparative HPLC. Their structures were elucidated based on spectroscopic methods including 1D and 2D NMR and HR-ESI-MS. Results Two new dihydro-β-agarofuran sesquiterpenes were isolated from the stems and leaves of M. chinense and identified as 1α,6β-dinicotinoyloxy-9α-acetoxy-dihydro- β-agarofuran (1) and 1α,6β-dinicotinoyloxy-9α-benzoyloxy-8α-hydroxydihydro-β-agarofuran (2). Conclusion Compounds 1 and 2 are new compounds, and named as monimins I and II, respectively.