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Objective: To investigate the birth defect condition in Haidian district of Beijing city, 61 272 live-born infants who were delivered in Haidian Maternal and Child Health Hospital from 2003 to the March of 2009 are analyzed. Methods: Data was collected from the hospital' s medical records and from the birth defect surveillance. Results: Among the newborns studied, 1 076 were found having birth defect (17.56‰). The most common birth defects are congenital heart defect, followed by dysmorphosis of external ear, polydactyly, hypospadia, cleft lip and palate. In addition, three birth defects that are not included in the birth defect surveillance list were enorchia, renal agenesis and giant hemangioma. The birth defect rates of preterm and small for gestational age infants are significantly higher than it of the term infants. The birth defect patterns for these two types of abnormal infants are distinct. Conclusion: We have determined the pattern of birth defects in Beijing, which may help in policy-making regarding the prevention and intervention of birth defects.
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OBJECTIVE To study the risk factors of neurosurgical postoperative intracranial infection.METHODS Totally 5405 patients who had a neurosurgical operation from 1996 to 2003 in our department were chosen(172(cases) with intracranial infection).Many risk factors were studied retrospectively,A data-base was set up with EXCEL,and Logistic regression was selected to analyze the factors which might cause infection.RESULTS The(analysis) of 5405 cases revealed that infection rate was closely related to the operation durations,CSF fistulae,(ventricle) drainage,the insertion of tubes,the approach to the post fossa,the complication from diabetes mellitus(DM),and open(craniocerebral) injuries.While had little effect of sex,age,the season,longer application of hormones before the operation,preoperative diseases,and longer application of antibiotics before or after the operation.(CONCLUSIONS) To decrease the infection rate,according the clinical experience,the operation should be finished as soon as possible,the suture should be done completely to prevent CSF fistulae,and the duration of the ventricle drainage should be controlled strictly.