RESUMEN
[Objective] To assess the safety of patients with pheochromocytoma receiving iodinated contrast media injection during enhanced CT examination.[Methods] The systolic pressure,diastolic pressure,heart rate of 205 patients with suspected diagnosis of adrenal pheochromocytoma were continuously recorded 10 minutes before the examination,and 5 minutes,10 minutes,20 minutes,30 minutes,and 24 hours after the examination.Among them,50 patients whose diagnosis were confirmed by pathology as pheochromocytoma were set as group A.Others were excluded pheochromocytoma and 50 were extracted from them and named as the control group(group B).The changes of blood pressure and heart rate were analyzed at different time points.[Results] The changes of blood pressure and heart rate before and after the examination in two groups showed no significant difference,as well as those at different time points between two groups.[Conclusions] Intravenous injection of low-osmolar iodinated contrast media does not induce changes of blood pressure and heart rate in pheochromocytoma patients.Pheochromocytoma patients have the same safety as patients with other adrenal carcinoma during enhanced CT examination.
RESUMEN
Objective To analyze the clinical characteristics of pneumomediastinum in patients with dermatomyositis and polymyositis for demonstrating its pathogenesis and for predicting its prognosis. Methods The clinical records of 96 patients with PM/DM were reviewed, focusing on for perdicting its pneumomediastinum. Five patients with pneumomediastinum are described in detail. Case reports of pneumomediastinum in PM/DM in English publications are reviewed. Results Five DM cases complicated by pneumomediastinum all had lung infections. Twenty-nine cases (including our five cases) of DM/PM with pneumomediastinum have taken methylprednisolone, four cases alive, and six died. Nine cases have taken CsA,seven cases alive and two died. Conclusion The infections was strongly suspected as being responsible for the pneumomediastinum. Methylprednisolone has poor effect. CsA can be an effective therapeutic agent in PM/DM.