RESUMEN
Objective: To study the features of spontaneous isolated superior mesenteric artery dissection (SISMAD) by unexpected detection of renal artery dual-source CT (DSCT) imaging in hypertension patients. Methods: A total of 4107 patients with suspected secondary hypertension received renal artery DSCT examination in our hospital from 2010-03 to 2015-04 were studied and SISMAD was unexpectedly found in 12 patients. There were 3 patients with mild abdominal pain and the rest without obvious abdominal symptoms. The position and length, true and false lumens, detached tunica intimal flap and branch involvement of dissection, intestinal wall edema and ileus were recorded. Results: SISMAD in all 12 (0.3%) patients were found unexpectedly. Axial CT with post-processing technique clearly displayed the ruptured tunica intimal orifice, true and false lumens, detached intimal flap; the branches were all originated from true lumen. According to Sakamoto classification, all 12 patients were belong to Type I as the true and false lumens were with an entry and re-entry respectively, no filling defect in false lumen. The distance from orifice of dissection to root of abdominal aorta was (26.7 ± 11.3) mm and the length of dissection was (35.1 ± 11.7) mm.There were 10 patients with aneurysmal expansion with the diameter of (11.9 ± 2.5) mm. Conclusion: Unexpected detection of SISMAD by renal artery CT imaging was about 0.3%, radiologist should pay special attention to find superior mesenteric artery dissection in hypertension patients.
RESUMEN
Objective To investigate the relationship between IL-10 SNPs and pulmonary tubercu-losis susceptibility.Methods Collected 104 blood samples of pulmonary tuberculosis patients as case group and 104 blood samples of healthy.To analyze genotype SNPs of IL-10-819 -1082 by genomic DNA extraction,PCR amplification and TOF mass spectrometry.Finally the differences of gene and the risk of pulmonary tuberculosis occurrence were analyzed.Results IL-10-819 C/C, C/T and T/T site genotype frequencies were not different between two groups( P >0.05).IL-10-1082 G/G、G/A、A/A site genotype frequencies were not different between two groups( P >0.05).In logistic multivariate regression analysis found that:be compared with IL-10-819 C/C, the risk carrying IL-10-819 C/T, T/T group respectively of pulmonary tuberculosis were OR =0.001(95%CI =0.511~1.921), P =0.977, OR =2.116(95%CI=0.263~1.219), P =0.146, without statistical significance.Be compared with IL-10-1082 A/A, the risk carrying IL-10-1082 G/A、G/G group respectively of pulmonary tuberculosis were OR =0.113(95%CI =0.540~2.393), P =0.737, OR =1.872(95%CI =0.275~1.258), P =0.171, without statisti-cal significance.Conclusions IL-10-819 and -1082 genotype and allele distribution are not different, the mutation of genotype is not correlation with pulmonary tuberculosis.