RESUMEN
It is a common way for estimating of time of death in forensic science by the extent of gastric emptying, but this method may be less accurate in sometimes. Here, we report 5 cases with significant delayed gastric emptying and made discussion about it.
Asunto(s)
Adulto , Anciano , Femenino , Humanos , Masculino , Persona de Mediana Edad , Muerte , Ingestión de Alimentos , Alimentos , Medicina Legal/métodos , Vaciamiento Gástrico , Motilidad Gastrointestinal/fisiología , Factores de TiempoRESUMEN
OBJECTIVE@#A rapid and selective method has been developed for the determination of propofol in blood by gas chromatography-mass spectrometry (GC-MS).@*METHODS@#The blood was extrasted with the solution of internal standard, the extracted residue was analyzed by gas chromatography-mass spectrometry using selected-ion monitoring mode.@*RESULTS@#The linear range was 0.1-10 microg/mL. The coefficient(R2) was 0.993 1. The detection limit was 0.05 microg/mL.@*CONCLUSION@#The method is simple and rapid, offering superior sensitivity and selectivity for propofol. The method can be used successfully during clinical and forensic toxicology.