1.
Chinese Pharmacological Bulletin
; (12): 52-61, 2021.
Artículo
en Chino
| WPRIM
| ID: wpr-1014293
RESUMEN
Aim To explore the biological role and related mechanism of rosuvastatin (RS) in mitochondrial damage of neurons after cerebral ischemia/reperfusion (CIR) through UCP2-SIRT3 signaling pathway. Methods Human neuroblastoma cell (SH-SY5Y cell) cerebral infarction reperfusion model (OGD/R) was established, different concentrations of RS (40 and 2. 5 (mol • L