RESUMEN
OBJECTIVE: To study the chemical constituents of Selaginella remotifolia Spring. METHODS: Fourteen biflavonoids were isolated from S. remotifolia by polyamide, Sephadex LH-20 column chromatography and/or Pre-HPLC. RESULTS: Their structures were identified by physiochemical properties, MS, and NMR as robustaflavone(1), robustaflavone-4'-methyl ether(2), (2''S)-2'', 3''-dihydrorobustaflavone-4'-methyl ether(3), (2S, 2''S)-tetrahydrorobustaflavone(4), amentoflavone(5), ametoflavone-7, 4'-dimethyl ether(6), amentoflavone-4', 7''-dimethyl ether(7), (2''S)-2'', 3''-dihydroamentoflavone(8), (2''S)-2'', 3''-dihydroamentoflavone-4'-methyl ether(9), (2S)-2, 3-dihydroamentoflavone (10), (2S) -2, 3-dihydroamentoflavone-4'-methyl ether (11), (2S)-2, 3-dihydroamentofla-vone-4'''-methyl ether(12), chamaeflavone A(13), and 8-8''-bi-kaempferol(14). CONCLUSION: All compounds were isolated from this plant for the first time and compounds 13 and 14 are isolated from this genus for the first time.