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1.
Immunological Journal ; (12): 110-112, 2001.
Artículo en Chino | WPRIM | ID: wpr-433888

RESUMEN

Objective To study how ConA actives macrophages in vivo to produce cytotoxic effectors and its phagocytic functions,and  cytotoxicity. Methods  ConA was intraperitoneally injected(ip). Cock red blood cells(cRBC) were used to evaluate MΦ phagocytic activity,and S180 cells as target cells to analyze MΦ dependent cytotoxicity(MTC).Nitric oxide(NO),TNF-α and IL-1 levels of MΦ cultural supernatant were measured using griess reagent,L929 cells MTT method and thymocytes proliferation test respectively. Results  ConA could promote MΦ to phagocytize cRBC and kill S180 cells,enhance the production of such factors as NO,TNF-α and IL-1 by MΦ. There was significant difference compared with PBS control group(P<0.01). Conclusions  ConA could stimulate MΦ to produce effectors, which mediate immune regulation of ConA to MΦ.

2.
Microbiology ; (12)1992.
Artículo en Chino | WPRIM | ID: wpr-683723

RESUMEN

We first study the photosensitization to bacteria and fungi with a definite structure, watersoluble porphyrin. We found that the porphyrin had strong sterilization on the Staphylococcus au- reus and Candida albicans. When the porphyrin concentrations increased, its sterilization strengthened. The sterilization was related to the photoradiating time. When photoradiating time was one hour, its sterilizing ability was the greatest. Its sterilizing ability was similar to the penicillin's.

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