Practice and exploration in the co-building of culture at large shelter hospitals by doctors and patients / 中华医院管理杂志

Hospital culture plays an important role in the orderly operation of large shelter hospitals as well as epidemic prevention and control.From April to May 2022, the shelter hospital of the National Convention and Exhibition Center(Shanghai) had created the large shelter hospital culture co-built by doctors and patients with a greater sense of belonging by taking measures such as joint party building between doctors and patients, giving play to the vanguard force of party members, carrying out various forms of cultural, sports and science popularization activities, encouraging enthusiastic patients to participate in activity planning, focusing on key groups, formulating shelter " residents convention", and so on. These measures ultimately formed cultural adaptation, cultural synchronization and cultural shaping, which were conducive to enhancing the empathy of doctors and patients, improving the effectiveness of medical implementation, and promoting the standardization of shelter management system. This harmonious, warm and autonomous culture co-built by doctors and patients effectively ensures the safe and orderly operation of the shelter hospital, and provides reference for the construction of the cultural system of large shelter hospitals in China.

RAGE, NF-kappaB, p21 expressions in mouse spiral ganglion cells / 临床耳鼻咽喉头颈外科杂志

OBJECTIVE@#To research advanced glycation end-product receptors (RAGE), NF-kappaB, p21 expressions in C57BL/6j mice cochlea spiral ganglion cells(SGC) ,and then to investigate the presbycusis pathogenesis.@*METHOD@#To take C57BL/6J mice:2 month 25,and 10 month 25. Histological sections were observed the SGC. RAGE, NF-kappaB, p21 were immunohistochemical in the SGC,with IPP6 to IOD.@*RESULT@#(1) The count SGCs of 10 month-old was obviously decreased comparing to 2 month-old, the count of 2 month SGC is 39 +/- 5, 10 month group is 20 +/- 6, P < 0.01; (2) RAGE, NF-kappaB, p21 expressed in spiral ganglion cell,different place with different age,and the means optical density in the 10 month are higher than the 2 month, respectively. The IOD of RAGE expression in 2 month SGC: 0.179 +/- 0.025, 10 month IOD: 0.308 +/- 0.050; The IOD of NF-kappaB expression in 2 month SGC: 0.181 +/- 0.045, 10 month IOD: 0.335 +/- 0.120; The IOD of p21 expression in 2 month SGC: 0.160 +/- 0.023, 10 month IOD: 0.365 +/- 0.031, compare with 2 group, respectively, P < 0.05, and the difference has statistics sense.@*CONCLUSION@#RAGE,NF-kappaB, p21 expressions are in SGCs and increases with the aging of SGCs, suppose RAGE, NF-kappaB, p21 may participate in the process of presbycusis pathogenesis.

Study of allergen skin prick tests on different region of forearm / 临床耳鼻咽喉头颈外科杂志

OBJECTIVE@#To investigate the variation on different regions of the forearm when taking the allergen skin prick tests(SPTs).@*METHOD@#Forty-one patients with hyper-reactive nasal symptoms were included. SPTs were done on the proximal, telecentric, middle region of right forearm and telecentric region of left forearm with house dust mite and histamine. The average diameter of wheal and the reactive grade were calculated and analyzed.@*RESULT@#The diameters of the wheal on equal position of two forearms were similar (P > 0.05). The intension of SPTs reaction decreased from proximal to telecentric region of the same forearm (P < 0.05).@*CONCLUSION@#The intension of SPTs reaction on different region of forearm are quite different, which should be noticed in clinical practice.

Efficacy evaluation of specific immunotherapy with standardized dermatophagoides pteronyssinus extract for allergic rhinitis accompanied with asthma / 临床耳鼻咽喉头颈外科杂志

Objective:To evaluate the efficacy of specific immunotherapy (SIT) with standardized dermatophagoides pteronyssinus extract for allergic rhinitis (AR)accompanied with asthma.Method:One hundred and fifty-five patients(40 AR with asthma, AR & asthma) in accordance with the inclusion criteria of SIT, were allocated to receive standardized Dermatophagoides pteronyssinus extract (SIT group, n=89) or medical treatment(control group, n=66). AR with or without asthma was observed separately. Symptom and medicine scores, quality of life were recorded and analyzed before and after 1 year treatment. Side effects were registered. Subjective evaluation of symptoms was made by the patients.Result:Rhinitis and asthma symptom scores, medicine scores and quality of life were greatly improved in SIT group of AR & asthma after 1 year, which were not significant changed in control group except for medicine scores. The subjective evaluation of symptoms was also significantly improved in SIT group. In patients of AR without asthma, the symptom scores, medicine scores and quality of life were both improved. The SIT group improved greater than that of control group.Conclusion:The clinical efficacy of patients with AR & asthma was not good with simple medical treatment, while great clinical efficacy could be acquired with SIT.

Efficacy evaluation of specific immunotherapy with standardized dermatophagoides pteronyssinus extract for allergic rhinitis accompanied with asthma / 临床耳鼻咽喉头颈外科杂志

OBJECTIVE@#To evaluate the efficacy of specific immunotherapy (SIT) with standardized dermatophagoides pteronyssinus extract for allergic rhinitis (AR)accompanied with asthma.@*METHOD@#One hundred and fifty-five patients (40 AR with asthma, AR & asthma) in accordance with the inclusion criteria of SIT, were allocated to receive standardized Dermatophagoides pteronyssinus extract (SIT group, n = 89) or medical treatment (control group, n = 66). AR with or without asthma was observed separately. Symptom and medicine scores, quality of life were recorded and analyzed before and after 1 year treatment. Side effects were registered. Subjective evaluation of symptoms was made by the patients.@*RESULT@#Rhinitis and asthma symptom scores, medicine scores and quality of life were greatly improved in SIT group of AR & asthma after 1 year, which were not significant changed in control group except for medicine scores. The subjective evaluation of symptoms was also significantly improved in SIT group. In patients of AR without asthma, the symptom scores, medicine scores and quality of life were both improved. The SIT group improved greater than that of control group.@*CONCLUSION@#The clinical efficacy of patients with AR & asthma was not good with simple medical treatment, while great clinical efficacy could be acquired with SIT.

Observation on cerebrovascular hemodynamic index in experimental atherosclerotic rabbits / 国际生物医学工程杂志

Objective To observe the changes of cerebrovascular hemodynamic index(CVHI) in atherosclerotic rabbits. Methods Twenty male New Zealand rabbits were randomly divided into two group: Twelve were atherosclerosis model (AS) group and eight were control group. Atherosclerosis model group were fed with high fat diet and control group were fed with ordinary diet. At 12th week, CVHI were measured in the common carotid artery with spectral analysis and the compliance of carotid was observed. Results In the AS group, the carotid artery maximal velocity (vmax) and minimal velocity (vmin) were significantly decreased (P

Study of Double Interventional Treatment(DIT) on Pulmonary Carcinoma Type PT4 / 介入放射学杂志

Purpose: To discuss the methods and the effects of DIT on pulmonary carcinoma Type PT4 Materials and methods: This Procedure was performed in 45 cases with Pulmonary Carcinoma Type PT4 using infusion of chemotherapeutical agent through catheterized bronchial and pulmonary arteries, bronchial artery and thoracic aorta or bronchial artery and intrapleural cavity respectevely on central pulmonary carcinomas complicating with metastasis in lung 15 cases, complete atelectasis 15 cases or ipsilateral hydrothorax 15 cases. Results: 7 cases were complete relaxed (CR15.6%); 13 partial relax ed (PR28.9%); 20 nochange (44. 4% ); 5 enlarged (11.1% ). Conclusion: The results showed this method is some what egnal to or ever in some aspects, prevalent over that of systematic chemotherapy theretore provides new scientific method for thel treatment of pulmonary carcinoma Type PT4.

The Changes of Prothrombin in the Patients with Hepatocellular Carcinoma Treated by Transcather Arterial Chemoembolization(TAE) and Intra-arterial Infusion (TAI) of Anti-cancerous Agents / 介入放射学杂志

The blood samples of hepatic arteries and peripheral veins of 65 cases of hepatocell ular carcinoma were studied.The results showed :1.The drop of plasma prekallikrein (PK), the elevation of fibrinogen degradation products (FDP) and the prolongation of prothrombin time(PT) were observed in three types (common, inflammatory and sclerosing) of hepatocellular carcinomas.2.The effect of TAE on PK was significant proportional to the treatment frequency.3.Same as the effect of TAI on the PT.4.The increasing frequency

Separation,culture and identification of neural stem cells from rat embryo / 第二军医大学学报

This study is to set up a method for separating,culturing and identifying neural stem cells from cortex in rat embryo,observing their characteristics of multipotentiality and differentiation in vitro. By using serum-free cell culturing and clone technology,the stem cells were isolated,cultured and passaged from cortex in 14-day old rat embryo. The expression of Nestin antigen of brain cells were investigated by immunocytochemistry and H-E staining. It proved that cells separated from cortex in rat embryo possessed the potential to form clones and express nestin special antigen,the differentiated cells could express special antigen of neurons,astrocytes,and oligodendrocytes,they were stem cells of central nervous system.