Clinical effects of sub-maximum ergometry exercise rehabilitation in patients with chronic obstructive pulmonary disease / 中国应用生理学杂志

<p><b>OBJECTIVE</b>To study the rehabilitation effects ergometry on COPD patients.</p><p><b>METHODS</b>Thirty COPD out-patients in our Hospital were randomly divided into 2 groups. Rehabilitation group, 15 patients, performed leg ergometry exercise of 80% peak Watt x 30min/d x 3d/w x 12w. Another 15 patients were control group without exercise. All patients received conventional therapy. Pulmonary function testing (PFT), cardiopulmonary exercise testing (CPET), arterial blood gas analysis (ABG), Borg and CAT sores were done at both baseline and 12 w.</p><p><b>RESULTS</b>There was no statistically difference in lung function testing, blood gas analysis and cardiopulmonary exercise test when pre- exercises between 2 sub-groups. The IC, peak VO2 and peak, W of rehabilitation group significantly increased (P < 0.05); and Borg and CAT.scores significantly decreased (P < 0.05) from baseline; and other PFT and ABG did not change (P > 0.05). While there was no difference in control group (P > 0.05).</p><p><b>CONCLUSION</b>Leg submaximal ergometry rehabilitation improves health condition and ameliorate dyspnea symptoms in COPD patients.</p>

Effects of tiotropium on pulmonary function and exercise tolerance in patients with chronic obstructive pulmonary disease / 上海第二医科大学学报

0.05). ConclusionThe present study confirms that tiotropium 18 ug once daily compare with ipratropium can reduce lung hyperinflation,ease exertional dyspnea and improve symptom-limited exercise tolerance in COPD patients.

Relationship between polymorphism of Aiolos exon 8+488C/T and bronchial asthma / 上海第二医科大学学报

0.05). Conclusion The exon 8+488C/T polymorphism of Aiolos gene exists in this population of Han ethnics,however,it is not associated with bronchial asthma.